Origin of antibiotics and antibiotic resistance, and their impacts on drug development: A narrative review

G Muteeb, MT Rehman, M Shahwan, M Aatif - Pharmaceuticals, 2023 - mdpi.com
Antibiotics have revolutionized medicine, saving countless lives since their discovery in the
early 20th century. However, the origin of antibiotics is now overshadowed by the alarming …

Carbonic anhydrase and bacterial metabolism: a chance for antibacterial drug discovery

C Capasso, CT Supuran - Expert Opinion on Therapeutic Patents, 2024 - Taylor & Francis
ABSTRACT Introduction Carbonic anhydrases (CAs, EC 4.2. 1.1) play a pivotal role in the
regulation of carbon dioxide, bicarbonate, and hydrogen ions within bacterial cells, ensuring …

Co-application of copper nanoparticles and metal tolerant Bacillus sp. for improving growth of spinach plants in chromium contaminated soil

A Ali, SMS Alghanem, HAS Al-Haithloul, S Muzammil… - Chemosphere, 2023 - Elsevier
Chromium (Cr) is classified as a toxic metal as it exerts harmful effects on plants and human
life. Bacterial-assisted nano-phytoremediation is an emerging and environment friendly …

WHO AWaRe classification for antibiotic stewardship: tackling antimicrobial resistance–a descriptive study from an English NHS Foundation Trust prior to and during …

R Abdelsalam Elshenawy, N Umaru… - Frontiers in …, 2023 - frontiersin.org
Antimicrobial resistance (AMR) is a silent and rapidly escalating pandemic, presenting a
critical challenge to global health security. During the pandemic, this study was undertaken …

Effect of nano-metal oxides (TiO2, MgO, CaO, and ZnO) on antibacterial property of (PEO/PEC-co-AAm) hydrogel synthesized by gamma irradiation

FI Abou El Fadl, DE Hegazy, NA Maziad… - International Journal of …, 2023 - Elsevier
The global threat of infectious diseases and antibiotic resistance calls for the development of
potent antimicrobial agents integrated with hydrogel for effective control and treatment …

[HTML][HTML] Antimicrobial resistance: impacts, challenges, and future prospects

SK Ahmed, S Hussein, K Qurbani, RH Ibrahim… - Journal of Medicine …, 2024 - Elsevier
Antimicrobial resistance (AMR) is a critical global health issue driven by antibiotic misuse
and overuse in various sectors, leading to the emergence of resistant microorganisms. The …

A South African Perspective on the Microbiological and Chemical Quality of Meat: Plausible Public Health Implications

CE Manyi-Loh, R Lues - Microorganisms, 2023 - mdpi.com
Meat comprises proteins, fats, vitamins, and trace elements, essential nutrients for the
growth and development of the body. The increased demand for meat necessitates the use …

Management of Neisseria gonorrhoeae infection: from drug resistance to drug repurposing

L Pisano, S Giovannuzzi… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Neisseria gonorrhoeae is a common sexually transmitted disease connected
with extensive drug resistance to many antibiotics. Presently, only expanded spectrum …

Novel therapeutic hybrid systems using hydrogels and nanotechnology: a focus on nanoemulgels for the treatment of skin diseases

K Sghier, M Mur, F Veiga, AC Paiva-Santos, PC Pires - Gels, 2024 - mdpi.com
Topical and transdermal drug delivery are advantageous administration routes, especially
when treating diseases and conditions with a skin etiology. Nevertheless, conventional …

New sulfonamide-tethered coumarin derivatives as potential DNA gyrase inhibitors: design, synthesis, antimicrobial evaluation, and in silico study

HM Abo-Salem, EAB Ali, SA El-Mowafi… - Journal of Molecular …, 2024 - Elsevier
A new series of coumarin-6-sulfonamide derivatives 3–16 have been synthesized via simple
and convenient coupling reaction of coumarin-6-sulfonyl chloride with different sulfa drugs …