The neurovascular unit–concept review

V Muoio, PB Persson, MM Sendeski - Acta physiologica, 2014 - Wiley Online Library
The cerebral hyperaemia is one of the fundamental mechanisms for the central nervous
system homeostasis. Due also to this mechanism, oxygen and nutrients are maintained in …

Hippocampal sclerosis in epilepsy: a neuropathology review

M Thom - Neuropathology and applied neurobiology, 2014 - Wiley Online Library
Hippocampal sclerosis (HS) is a common pathology encountered in mesial temporal lobe
epilepsy (MTLE) as well as other epilepsy syndromes and in both surgical and post‐mortem …

Overview and introduction: the blood–brain barrier in health and disease

NJ Abbott, A Friedman - Epilepsia, 2012 - Wiley Online Library
This article introduces the special issue on “Blood–Brain Barrier and Epilepsy.” We review
briefly current understanding of the structure and function of the blood–brain barrier (BBB) …

Multifunctional role of astrocytes as gatekeepers of neuronal energy supply

JL Stobart, CM Anderson - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Dynamic adjustments to neuronal energy supply in response to synaptic activity are critical
for neuronal function. Glial cells known as astrocytes have processes that ensheath most …

Blood–brain barrier dysfunction, seizures and epilepsy

EA Van Vliet, E Aronica, JA Gorter - Seminars in cell & Developmental …, 2015 - Elsevier
The blood–brain barrier (BBB) is a dynamic and complex system which separates the brain
from the blood. It helps to maintain the homeostasis of the brain, which is essential for …

Astrocytes as new targets to improve cognitive functions

G Dallérac, N Rouach - Progress in neurobiology, 2016 - Elsevier
Astrocytes are now viewed as key elements of brain wiring as well as neuronal
communication. Indeed, they not only bridge the gap between metabolic supplies by blood …

Role of astrocytes in epilepsy

DK Binder, C Steinhäuser - Astrocytes in (Patho) physiology of the nervous …, 2009 - Springer
Epilepsy, affecting about 1% of the population, comprises a group of disorders of the brain
characterized by the periodic and unpredictable occurrence of seizures. Epilepsy is a major …

Epilepsies associated with hippocampal sclerosis

F Cendes, AC Sakamoto, R Spreafico… - Acta …, 2014 - Springer
Hippocampal sclerosis (HS) is considered the most frequent neuropathological finding in
patients with mesial temporal lobe epilepsy (MTLE). Hippocampal specimens of …

Structure and function of the blood–brain barrier (BBB)

F Benz, S Liebner - Physiology, Pharmacology and Pathology of the Blood …, 2020 - Springer
The blood-brain barrier (BBB) protects the vertebrate central nervous system from harmful
blood-borne, endogenous and exogenous substances to ensure proper neuronal function …

Role of blood–brain barrier in temporal lobe epilepsy and pharmacoresistance

EA Van Vliet, E Aronica, JA Gorter - Neuroscience, 2014 - Elsevier
Temporal lobe epilepsy (TLE) is the most common form of focal epilepsies in adults. It is
often initiated by an insult or brain injury which triggers a series of alterations which …