[HTML][HTML] Nrf2-mediated anti-inflammatory polarization of macrophages as therapeutic targets for osteoarthritis

L Wang, C He - Frontiers in immunology, 2022 - frontiersin.org
Macrophages are the most abundant immune cells within the synovial joints, and also the
main innate immune effector cells triggering the initial inflammatory responses in the …

The roles of macrophage polarization in the host immune response to sepsis

X Chen, Y Liu, Y Gao, S Shou, Y Chai - International immunopharmacology, 2021 - Elsevier
Sepsis is a life-threatening clinical syndrome caused by infection. Its pathogenesis is
complex and entails coagulation dysfunction, inflammation, and immune disorders …

Understanding the mysterious M2 macrophage through activation markers and effector mechanisms

T Rőszer - Mediators of inflammation, 2015 - Wiley Online Library
The alternatively activated or M2 macrophages are immune cells with high phenotypic
heterogeneity and are governing functions at the interface of immunity, tissue homeostasis …

[HTML][HTML] Anti-inflammatory microRNAs and their potential for inflammatory diseases treatment

A Tahamtan, M Teymoori-Rad, B Nakstad… - Frontiers in …, 2018 - frontiersin.org
Inflammation is a complicated biological and pathophysiological cascade of responses to
infections and injuries, and inflammatory mechanisms are closely related to many diseases …

Macrophage polarization and allergic asthma

A Saradna, DC Do, S Kumar, QL Fu, P Gao - Translational Research, 2018 - Elsevier
Allergic asthma is associated with airway inflammation and airway hyperresponsiveness.
Macrophage polarization has been shown to have a profound impact on asthma …

MiRNA-mediated macrophage polarization and its potential role in the regulation of inflammatory response

K Essandoh, Y Li, J Huo, GC Fan - Shock, 2016 - journals.lww.com
Monocytes and macrophages are important components of the immune system, specialized
in either removing pathogens as part of innate immunity or contributing to adaptive immunity …

Macrophage polarization and meta-inflammation

C Li, MM Xu, K Wang, AJ Adler, AT Vella, B Zhou - Translational Research, 2018 - Elsevier
Chronic overnutrition and obesity induces low-grade inflammation throughout the body.
Termed “meta-inflammation,” this chronic state of inflammation is mediated by macrophages …

[HTML][HTML] Extracellular vesicles secreted by hypoxia pre-challenged mesenchymal stem cells promote non-small cell lung cancer cell growth and mobility as well as …

W Ren, J Hou, C Yang, H Wang, S Wu, Y Wu… - Journal of Experimental …, 2019 - Springer
Objective To investigate the lung cancer-promoting mechanism of mesenchymal stem cell-
secreted extracellular vesicles (MSC-EV). Methods EV were isolated from culture media of …

[HTML][HTML] A narrative review of tumor-associated macrophages in lung cancer: regulation of macrophage polarization and therapeutic implications

SS Sedighzadeh, AP Khoshbin, S Razi… - … lung cancer research, 2021 - ncbi.nlm.nih.gov
Lung cancer is the deadliest malignancy worldwide. An inflammatory microenvironment is a
key factor contributing to lung tumor progression. Tumor-Associated Macrophages (TAMs) …

CSF1R‐and SHP2‐inhibitor‐loaded nanoparticles enhance cytotoxic activity and phagocytosis in tumor‐associated macrophages

A Ramesh, S Kumar, D Nandi, A Kulkarni - Advanced Materials, 2019 - Wiley Online Library
Immune modulation of macrophages has emerged as an attractive approach for anti‐cancer
therapy. However, there are two main challenges in successfully utilizing macrophages for …