[HTML][HTML] A comprehensive analysis and anti-cancer activities of quercetin in ROS-mediated cancer and cancer stem cells
Reactive oxygen species (ROS) induce carcinogenesis by causing genetic mutations,
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
activating oncogenes, and increasing oxidative stress, all of which affect cell proliferation …
[HTML][HTML] Advanced implications of nanotechnology in disease control and environmental perspectives
Nanotechnology encompasses a wide range of devices derived from biology, engineering,
chemistry, and physics, and this scientific field is composed of great collaboration among …
chemistry, and physics, and this scientific field is composed of great collaboration among …
[HTML][HTML] Amentoflavone derivatives significantly act towards the main protease (3CLPRO/MPRO) of SARS-CoV-2: in silico admet profiling, molecular docking …
SARS-CoV-2 is the foremost culprit of the novel coronavirus disease 2019 (nCoV-19 and/or
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
simply COVID-19) and poses a threat to the continued life of humans on the planet and …
Natural flavonoids effectively block the CD81 receptor of hepatocytes and inhibit HCV infection: A computational drug development approach
Hepatitis C virus (HCV) infection is a major public health concern, and almost two million
people are infected per year globally. This is occurred by the diverse spectrum of viral …
people are infected per year globally. This is occurred by the diverse spectrum of viral …
[HTML][HTML] Study of MDM2 as Prognostic Biomarker in Brain-LGG Cancer and Bioactive Phytochemicals Inhibit the p53-MDM2 Pathway: A Computational Drug …
An evaluation of the expression and predictive significance of the MDM2 gene in brain lower-
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
grade glioma (LGG) cancer was carried out using onco-informatics pipelines. Several …
Molecular Dynamics Simulation and Pharmacoinformatic Integrated Analysis of Bioactive Phytochemicals from Azadirachta indica (Neem) to Treat Diabetes Mellitus
A Abdullah, P Biswas, M Sahabuddin… - Journal of …, 2023 - Wiley Online Library
Diabetes mellitus is a chronic hormonal and metabolic disorder in which our body cannot
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
generate necessary insulin or does not act in response to it, accordingly, ensuing in …
[HTML][HTML] Investigating the anticancer potential of salvicine as a modulator of topoisomerase II and ROS signaling cascade
Salvicine is a new diterpenoid quinone substance from a natural source, specifically in a
Chinese herb. It has powerful growth-controlling abilities against a broad range of human …
Chinese herb. It has powerful growth-controlling abilities against a broad range of human …
[HTML][HTML] Toward the identification of natural antiviral drug candidates against merkel cell polyomavirus: computational drug design approaches
Merkel cell carcinoma (MCC) is a rare form of aggressive skin cancer mainly caused by
Merkel cell polyomavirus (MCPyV). Most MCC tumors express MCPyV large T (LT) antigens …
Merkel cell polyomavirus (MCPyV). Most MCC tumors express MCPyV large T (LT) antigens …
[HTML][HTML] Evaluating the anti-urolithiasis potential of Ficus religiosa seed GC MS evaluated phytoconstituents based on their in-vitro antioxidant properties and in-silico …
Background Urolithiasis, the deposit of stones in the urinary tract is a pertinent clinical issue
in daily practice that imposes a burden on the human health system. Ficus religiosa plant …
in daily practice that imposes a burden on the human health system. Ficus religiosa plant …
Drug repurposing and systems biology approaches of Enzastaurin can target potential biomarkers and critical pathways in colorectal Cancer
Colorectal cancer (CRC) is a severe health concern that results from a cocktail of genetic,
epigenetic, and environmental abnormalities. Because it is the second most lethal …
epigenetic, and environmental abnormalities. Because it is the second most lethal …