A review of inactivated COVID-19 vaccine development in China: focusing on safety and efficacy in special populations

L Hu, J Sun, Y Wang, D Tan, Z Cao, L Gao, Y Guan… - Vaccines, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), has been widespread globally, and …

Hyperimmune Plasma and Immunoglobulins against COVID-19: a narrative review

M Franchini, D Focosi - Life, 2024 - mdpi.com
Since late 2019, the new SARS-CoV-2 virus belonging to the Coronaviridae family has been
responsible for COVID-19 pandemic, a severe acute respiratory syndrome. Several antiviral …

Safety and efficacy of inhaled IBIO123 for mild-to-moderate COVID-19: a randomised, double-blind, dose-ascending, placebo-controlled, phase 1/2 trial

B Maranda, SM Labbé, M Lurquin… - The Lancet Infectious …, 2024 - thelancet.com
Background COVID-19 severity is associated with its respiratory manifestations. Neutralising
antibodies against SARS-CoV-2 administered systemically have shown clinical efficacy …

Hybrid Immunity Improves the Immune Response after the Fourth COVID-19 Vaccine Dose in Individuals with Medical Conditions Predisposing to Severe COVID-19

N Ekström, TM Leino, A Juutinen, T Lehtonen, A Haveri… - Vaccines, 2024 - mdpi.com
Data on immune responses following COVID-19 booster vaccinations and subsequent
infections in the immunocompromised are limited. We studied antibody responses after the …

Potency and durability of T and B cell immune responses after homologous and heterologous vector delivery of a trimer-stabilized, membrane-displayed HIV-1 clade …

B Perdiguero, A Hauser, CE Gómez… - Frontiers in …, 2023 - frontiersin.org
Introduction The generation of an HIV-1 vaccine able to induce long-lasting protective
immunity remains a main challenge. Here, we aimed to modify next-generation soluble …

Production and Immunogenicity Assessment of LTp50: An Escherichia coli-Made Chimeric Antigen Targeting S1- and S2-Epitopes from the SARS-CoV-2/BA.5 Spike …

A Wong-Arce, O Gonzalez-Ortega… - Pharmaceuticals, 2024 - mdpi.com
Subunit vaccines stand as a leading approach to expanding the current portfolio of vaccines
to fight against COVID-19, seeking not only to lower costs but to achieve long-term immunity …

A pseudovirus-based neutralization assay for SARS-COV-2 variants: A rapid, cost-effective, BSL-2–based high-throughput assay useful for vaccine immunogenicity …

Z Cai, R Kalkeri, M Zhu, S Cloney-Clark, B Haner… - Microorganisms, 2024 - mdpi.com
Neutralizing antibody responses from COVID-19 vaccines are pivotal in conferring
protection against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Effective …

SARS-CoV-2 spike-FLIPr fusion protein plus lipidated FLIPr protects against various SARS-CoV-2 variants in hamsters

MS Hsieh, CW Hsu, HC Liao, CL Lin… - Journal of …, 2024 - Am Soc Microbiol
Vaccine-induced mucosal immunity and broad protective capacity against various severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants remain inadequate …

Viral Epitope Scanning Reveals Correlation between Seasonal HCoVs and SARS-CoV-2 Antibody Responses among Cancer and Non-Cancer Patients

SJ Lidenge, D Yalcin, SJ Bennett, O Ngalamika… - Viruses, 2024 - mdpi.com
Seasonal coronaviruses (HCoVs) are known to contribute to cross-reactive antibody (Ab)
responses against SARS-CoV-2. While these responses are predictable due to the high …

A community study of neutralizing antibodies against SARS-CoV-2 in China

Y Lv, L Huang, J Wang, H He, L Song, J He… - Frontiers in …, 2023 - frontiersin.org
Background The immune background of the overall population before and after the outbreak
of SARS-CoV-2 in China remains unexplored. And the level of neutralizing antibodies is a …