Concise review: MSC adhesion cascade—insights into homing and transendothelial migration

F Nitzsche, C Müller, B Lukomska, J Jolkkonen… - Stem …, 2017 - academic.oup.com
Mesenchymal stem cells (MSCs) are promising candidates for adult cell therapies in
regenerative medicine. To fully exert their potential, efficient homing and migration toward …

Mesenchymal stem cell migration during bone formation and bone diseases therapy

P Su, Y Tian, C Yang, X Ma, X Wang, J Pei… - International journal of …, 2018 - mdpi.com
During bone modeling, remodeling, and bone fracture repair, mesenchymal stem cells
(MSCs) differentiate into chondrocyte or osteoblast to comply bone formation and …

Improved therapeutics of modified mesenchymal stem cells: an update

DKW Ocansey, B Pei, Y Yan, H Qian, X Zhang… - Journal of translational …, 2020 - Springer
Abstract Background Mesenchymal stromal cells (MSCs) have attracted intense interest due
to their powerful intrinsic properties of self-regeneration, immunomodulation and multi …

Chondrogenic primed extracellular vesicles activate miR-455/SOX11/FOXO axis for cartilage regeneration and osteoarthritis treatment

Y Sun, J Zhao, Q Wu, Y Zhang, Y You… - npj Regenerative …, 2022 - nature.com
Osteoarthritis (OA) is the leading cause of disability worldwide. Considerable progress has
been made using stem-cell-derived therapy. Increasing evidence has demonstrated that the …

SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair

Q Miao, MC Hill, F Chen, Q Mo, AT Ku, C Ramos… - Nature …, 2019 - nature.com
Tissue injury induces changes in cellular identity, but the underlying molecular mechanisms
remain obscure. Here, we show that upon damage in a mouse model, epidermal cells at the …

[HTML][HTML] Identification of novel genes in aging osteoblasts using next-generation sequencing and bioinformatics

YJ Chen, WA Chang, MS Huang, CH Chen, KY Wang… - Oncotarget, 2017 - ncbi.nlm.nih.gov
During the aging process, impaired osteoblastic function is one key factor of imbalanced
bone formation and age-related bone loss. The aim of this study is to explore the …

SOX11 promotes tumor protective microenvironment interactions through CXCR4 and FAK regulation in mantle cell lymphoma

P Balsas, J Palomero, Á Eguileor… - Blood, The Journal …, 2017 - ashpublications.org
SOX11 overexpression in mantle cell lymphoma (MCL) has been associated with more
aggressive behavior and worse outcome. However, SOX11 oncogenic pathways driving …

Mesenchymal stem cells and MSCs-derived extracellular vesicles in infectious diseases: From basic research to clinical practice

N Yudintceva, N Mikhailova, V Fedorov… - Bioengineering, 2022 - mdpi.com
Mesenchymal stem cells (MSCs) are attractive in various fields of regenerative medicine due
to their therapeutic potential and complex unique properties. Basic stem cell research and …

Recent advances in bone-targeted therapy

C Shi, T Wu, Y He, Y Zhang, D Fu - Pharmacology & therapeutics, 2020 - Elsevier
The coordination between bone resorption and bone formation plays an essential role in
keeping the mass and microstructure integrity of the bone in a steady state. However, this …

SOX family transcription factors as therapeutic targets in wound healing: A comprehensive review

P Ye, R Gu, H Zhu, J Chen, F Han, X Nie - International Journal of …, 2023 - Elsevier
The SOX family plays a vital role in determining the fate of cells and has garnered attention
in the fields of cancer research and regenerative medicine. It also shows promise in the …