Single dose of a VSV-based vaccine rapidly protects macaques from Marburg virus disease

A Marzi, A Jankeel, AR Menicucci, J Callison… - Frontiers in …, 2021 - frontiersin.org
Marburg virus (MARV) is a member of the filovirus family that causes hemorrhagic disease
with high case fatality rates. MARV is on the priority list of the World Health Organization for …

The discovery and development of novel treatment strategies for filoviruses

SB Bradfute - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction Filoviruses are negative-stranded, enveloped RNA viruses that can cause
hemorrhagic fever in humans and include Ebola and Marburg viruses. Lethality rates can …

History and impact of the mouse-adapted Ebola virus model

SB Bradfute - Antiviral Research, 2023 - Elsevier
Ebola virus (EBOV) is a member of the filoviridae family, which are comprised of negative
sense, enveloped RNA hemorrhagic fever viruses that can cause severe disease and high …

Antiviral nanobiologic therapy remodulates innate immune responses to highly pathogenic coronavirus

X Liu, L Yuan, J Chen, Y Zhang, P Chen… - Advanced …, 2023 - Wiley Online Library
Highly pathogenic coronavirus (CoV) infection induces a defective innate antiviral immune
response coupled with the dysregulated release of proinflammatory cytokines and finally …

Evaluation of favipiravir in the treatment of COVID-19 based on the real-world

W Deng, C Yang, S Yang, H Chen, Z Qiu… - Expert review of anti …, 2022 - Taylor & Francis
Background The role of favipiravir (FVP) as a COVID-19 treatment is recognized but not fully
elucidated. We aimed to evaluate whether FVP has definite clinical efficacy and safety in the …

Single-shot ChAd3-MARV vaccine in modified formulation buffer shows 100% protection of NHPs

CL Finch, TH King, KJ Alfson, KA Albanese, JNP Smith… - Vaccines, 2022 - mdpi.com
Marburg virus (MARV) is a virus of high human consequence with a case fatality rate of 24–
88%. The global health and national security risks posed by Marburg virus disease (MVD) …

Early Sertoli cell gene expression regulates pathogenesis in response to Ebola virus

AL Webb, BG Schindell, G Soule, AB Siddik… - 2023 - researchsquare.com
Ebola virus (EBOV) persists and actively replicates in the reproductive tract of up to 50% of
male disease survivors six month after infection1. Persistent EBOV infections are usually …

[PDF][PDF] Single-Shot ChAd3-MARV Vaccine in Modified Formulation Buffer Shows 100% Protection of NHPs. Vaccines 2022, 10, 1935

CL Finch, TH King, KJ Alfson, KA Albanese, JNP Smith… - 2022 - academia.edu
Marburg virus (MARV) is a virus of high human consequence with a case fatality rate of 24–
88%. The global health and national security risks posed by Marburg virus disease (MVD) …