Antidepressant medications in dementia: evidence and potential mechanisms of treatment-resistance

H Costello, JP Roiser, R Howard - Psychological Medicine, 2023 - cambridge.org
Depression in dementia is common, disabling and causes significant distress to patients and
carers. Despite widespread use of antidepressants for depression in dementia, there is no …

Neuroimaging correlates of depression after traumatic brain injury: a systematic review

GC Medeiros, C Twose, A Weller… - Journal of …, 2022 - liebertpub.com
Depression is the most frequent neuropsychiatric complication after traumatic brain injury
(TBI) and is associated with poorer outcomes. Neuroimaging has the potential to improve …

[HTML][HTML] Barriers to genetic testing in clinical psychiatry and ways to overcome them: from clinicians' attitudes to sociocultural differences between patients across the …

J Pinzón-Espinosa, M van der Horst, J Zinkstok… - Translational …, 2022 - nature.com
Genetic testing has evolved rapidly over recent years and new developments have the
potential to provide insights that could improve the ability to diagnose, treat, and prevent …

Lifetime and current depression in the German National Cohort (NAKO)

F Streit, L Zillich, J Frank, L Kleineidam… - The World Journal of …, 2023 - Taylor & Francis
Objectives The present study introduces the assessment of depression and depressive
symptoms in the German National Cohort (NAKO), a population-based mega cohort …

Men's depression, externalizing, and DSM-5-TR: primary signs and symptoms or co-occurring symptoms?

S Rice, Z Seidler, D Kealy, J Ogrodniczuk… - Harvard Review of …, 2022 - journals.lww.com
Major depressive disorder (MDD) is a highly hetero-geneous diagnosis wherein the nine
MDD criterion signs and symptoms reflect 256 unique symptom combinations. 1 …

The political consequences of depression: how conspiracy beliefs, participatory inclinations, and depression affect support for political violence

MA Baum, JN Druckman, MD Simonson… - American journal of …, 2024 - Wiley Online Library
Depression can affect individuals' attitudes by enhancing cognitive biases and altering
perceptions of control. We investigate the relationship between depressive symptoms and …

Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice

H Li, A Kawatake-Kuno, H Inaba, Y Miyake, Y Itoh… - Neuron, 2024 - cell.com
Chronic stress is a major risk factor for psychiatric disorders, including depression. Although
depression is a highly heterogeneous syndrome, it remains unclear how chronic stress …

[HTML][HTML] Predictive biosignature of major depressive disorder derived from physiological measurements of outpatients using machine learning

N Ricka, G Pellegrin, DA Fompeyrine, B Lahutte… - Scientific Reports, 2023 - nature.com
Abstract Major Depressive Disorder (MDD) has heterogeneous manifestations, leading to
difficulties in predicting the evolution of the disease and in patient's follow-up. We aimed to …

[HTML][HTML] Adaptation of lipid profiling in depression disease and treatment: A critical review

B Pinto, T Conde, I Domingues… - International Journal of …, 2022 - mdpi.com
Major depressive disorder (MDD), also called depression, is a serious disease that impairs
the quality of life of patients and has a high incidence, affecting approximately 3.8% of the …

[HTML][HTML] Integrating genetics and transcriptomics to study major depressive disorder: a conceptual framework, bioinformatic approaches, and recent findings

EM Hicks, C Seah, A Cote, S Marchese… - Translational …, 2023 - nature.com
Major depressive disorder (MDD) is a complex and heterogeneous psychiatric syndrome
with genetic and environmental influences. In addition to neuroanatomical and circuit-level …