Barrett's esophagus is an intestine-like metaplasia and precursor of esophageal
adenocarcinoma. Triggered by gastroesophageal reflux disease, the origin of this …

Background Villin is a protein of the brush border of epithelial cells, which is used as an
immunohistochemical marker for colorectal and gastrointestinal neoplasms. However, other …

Simple Summary Oesophago-gastric cancers are associated with poor survival due to late
diagnosis. By the time patients present to their doctor, there is a high chance the disease …

Background Gastroesophageal reflux disease (GERD) is associated with impaired epithelial
barrier function that is regulated by cell-cell contacts. The aim of the study was to investigate …

Background Claudins are a family of integral membrane proteins and are components of
tight junctions (TJs). Many TJ proteins are known to tighten the cell structure and maintain a …

Introduction Recently, we showed that the length of cardiac mucosa in healthy volunteers
correlated with age and obesity. We have now examined the immunohistological …

Objective: To determine whether CDX2 and villin protein expression are associated with
intestinal metaplasia (IM) in gastric cardiac mucosa and to explore the relationship with …

LI-cadherin belongs to the so called 7D-cadherins, exceptional members of the cadherin
superfamily which are characterized by seven extracellular cadherin repeats and a small …

Aims Recently, we described a series of pancreatic neuroendocrine tumours (Pan NET s)
featuring prominent stromal fibrosis, which we called sclerosing Pan NET s. The aim of this …

Background Histopathologic differentiation between the stages of Barrett's carcinogenesis is
often challenging. Liver–intestine (LI)-cadherin, an intestine-specific marker, is involved in …