Psychopathy

SA De Brito, AE Forth, AR Baskin-Sommers… - Nature Reviews …, 2021 - nature.com
Psychopathy is a personality disorder characterized by a constellation of affective,
interpersonal, lifestyle and antisocial features whose antecedents can be identified in a …

Precision behavioral phenotyping as a strategy for uncovering the biological correlates of psychopathology

J Tiego, EA Martin, CG DeYoung, K Hagan… - Nature mental …, 2023 - nature.com
Our capacity to measure diverse aspects of human biology has developed rapidly in the past
decades, but the rate at which these techniques have generated insights into the biological …

[HTML][HTML] Acute blood biomarker profiles predict cognitive deficits 6 and 12 months after COVID-19 hospitalization

M Taquet, Z Skorniewska, A Hampshire… - Nature medicine, 2023 - nature.com
Post-COVID cognitive deficits, including 'brain fog', are clinically complex, with both objective
and subjective components. They are common and debilitating, and can affect the ability to …

A transdiagnostic network for psychiatric illness derived from atrophy and lesions

JJ Taylor, C Lin, D Talmasov, MA Ferguson… - Nature human …, 2023 - nature.com
Psychiatric disorders share neurobiology and frequently co-occur. This neurobiological and
clinical overlap highlights opportunities for transdiagnostic treatments. In this study, we used …

Cell type-specific manifestations of cortical thickness heterogeneity in schizophrenia

MA Di Biase, MP Geaghan, WR Reay, J Seidlitz… - Molecular …, 2022 - nature.com
Brain morphology differs markedly between individuals with schizophrenia, but the cellular
and genetic basis of this heterogeneity is poorly understood. Here, we sought to determine …

Shared and specific patterns of structural brain connectivity across affective and psychotic disorders

J Repple, M Gruber, M Mauritz, SC de Lange… - Biological …, 2023 - Elsevier
Background Altered brain structural connectivity has been implicated in the pathophysiology
of psychiatric disorders including schizophrenia (SZ), bipolar disorder (BD), and major …

White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis

MA Di Biase, S Cetin-Karayumak, AE Lyall… - Molecular …, 2021 - nature.com
Subtle alterations in white matter microstructure are observed in youth at clinical high risk
(CHR) for psychosis. However, the timing of these changes and their relationships to the …

Linking polygenic risk of schizophrenia to variation in magnetic resonance imaging brain measures: a comprehensive systematic review

H Jameei, D Rakesh, A Zalesky, MJ Cairns… - Schizophrenia …, 2024 - academic.oup.com
Background and hypothesis Schizophrenia is highly heritable, with a polygenic effect of
many genes conferring risk. Evidence on whether cumulative risk also predicts alterations in …

Giant ankyrin-B mediates transduction of axon guidance and collateral branch pruning factor sema 3A

BA Creighton, S Afriyie, D Ajit, CR Casingal, KM Voos… - Elife, 2021 - elifesciences.org
Variants in the high confident autism spectrum disorder (ASD) gene ANK2 target both
ubiquitously expressed 220 kDa ankyrin-B and neurospecific 440 kDa ankyrin-B (AnkB440) …

The schizophrenia syndrome, circa 2024: What we know and how that informs its nature

R Tandon, H Nasrallah, S Akbarian… - Schizophrenia …, 2024 - Elsevier
With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …