Antimicrobial peptides (AMPs) are regarded as a new generation of antibiotics. Besides
antimicrobial activity, AMPs also have antibiofilm, immune-regulatory, and other activities …

The advent of multidrug resistance among pathogenic bacteria has attracted great attention
worldwide. As a response to this growing challenge, diverse studies have focused on the …

Translocation of cell-penetrating peptides is often promoted by increased content of arginine
or other guanidinium groups. However, relatively little research has considered the role of …

In the last decades, the indiscriminate use of conventional antibiotics has generated high
rates of microbial resistance. This situation has increased the need for obtaining new …

The rise of antibiotic resistant bacteria due to overuse and misuse of antibiotics in medicine
and dentistry is a growing concern. New approaches are needed to combat antibiotic …

Much of the work probing antimicrobial peptide (AMP) mechanisms has focussed on how
these molecules permeabilize lipid bilayers. However, AMPs must also traverse a variety of …

Amphibian skin is a rich source of natural compounds with diverse antimicrobial and
immune defense properties. Our previous studies showed that the frog skin secretions …

Tunicates have been used as primitive models for understanding cell-mediated and humoral
immunity. Clavanin A (ClavA) is one member of a family of antimicrobial peptides produced …

Oestrogen inhibits bone resorption, at least in part, by regulating the production of several
cytokines, including interleukin-6 (IL-6), IL-1, receptor activator of nuclear factor kappaB …

To explore the potential intracellular mechanism of the antimicrobial peptide HJH-3 in killing
Salmonella, a DNA blocking test and scanning electron microscopy (SEM) were used to …