Aims We aimed to clarify the extent to which cardiac and peripheral impairments to oxygen
delivery and utilization contribute to exercise intolerance and risk for adverse events, and …

Obesity is associated with incident heart failure (HF), independent of other cardiovascular
risk factors. Despite rising rates of both obesity and incident HF, the associations remain …

Aims Both low and high body mass index (BMI) are associated with poor heart failure
outcomes. Whether BMI modifies benefits of sodium–glucose cotransporter 2 inhibitors …

The purpose of this study was to determine the cardiovascular consequences elicited by
activation of the inspiratory muscle metaboreflex in patients with heart failure with preserved …

Abstract In all cases, Heart Failure (HF) affects the mental health and consequently the QoL
of patients to a varying extent. This study aimed to evaluate the quality of life of patients with …

Aims There is little information about the influence of gender on quality of life (QoL) in heart
failure. The purpose of this study was to evaluate whether the health‐related QoL gap …

Despite a paucity of pharmaceutical therapies proven to improve outcomes in HFpEF,
nonpharmaceutical therapies through exercise and dietary interventions have demonstrated …

Background The relationship between physical activity (PA), exercise capacity, and quality
of life (QOL) in obese heart failure with preserved ejection fraction is poorly understood …

Objective To determine whether nitrite can enhance exercise training (ET) effects in heart
failure with preserved ejection fraction (HFpEF). Methods In this multicenter, double-blind …

The prevalence of obesity is rapidly increasing in the Western World, and by 2030, it is
estimated that one out of two adults in the United States will be obese. 1 Obesity is clearly …