Exploring the pharmacological mechanisms and key active ingredients of total flavonoids from Lamiophlomis rotata (Benth.) Kudo against rheumatoid arthritis based …
H Zhan, R Chen, M Zhong, G Wang, G Jiang… - Journal of …, 2023 - Elsevier
Abstract Ethnopharmacological relevance Lamiophlomis rotata (Benth.) Kudo (LR,
Lamiaceae) is a traditional Tibetan medicinal material in China. Tibetan medicine classic …
Lamiaceae) is a traditional Tibetan medicinal material in China. Tibetan medicine classic …
A polysaccharide from Alhagi honey protects the intestinal barrier and regulates the Nrf2/HO-1-TLR4/MAPK signaling pathway to treat alcoholic liver disease in mice
J Song, X Zhao, J Bo, Z Lv, G Li, Y Chen, J Liang… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance According to the theory of traditional Chinese medicine,
the main factors related to alcoholic liver disease (ALD) are qi stagnation and blood stasis of …
the main factors related to alcoholic liver disease (ALD) are qi stagnation and blood stasis of …
Cepharanthine Exerts Antioxidant and Anti-Inflammatory Effects in Lipopolysaccharide (LPS)-Induced Macrophages and DSS-Induced Colitis Mice
G Chen, D Wen, L Shen, Y Feng, Q Xiong, P Li, Z Zhao - Molecules, 2023 - mdpi.com
Cepharanthine (CEP), a biscoclaurine alkaloid extracted from Stephania cepharantha
Hayata, has been widely used for the treatment of various acute and chronic diseases …
Hayata, has been widely used for the treatment of various acute and chronic diseases …
The protective effect and mechanism of mangiferin on D‐galactose‐induced oxidative stress and cognitive impairment in aging mice by an integrated network …
J Zhang, Y Chen, Z Wang, W Zhou, H Ullah… - Food …, 2023 - Wiley Online Library
Mangiferin (MAN) was a natural bioactive xanthone with remarkable antioxidative, anti‐
inflammatory, and antiapoptotic effects. The purpose of this study to determine the protective …
inflammatory, and antiapoptotic effects. The purpose of this study to determine the protective …
Rutin targets AKT to inhibit ferroptosis in ventilator‐induced lung injury
S Chen, Z Li, Y Xiao, Z Zhou, Q Zhan… - Phytotherapy …, 2024 - Wiley Online Library
Our previous research confirmed that rutin reduced ventilator‐induced lung injury (VILI) in
mice. Ferroptosis has been reported to participate in the pathogenic process of VILI. We will …
mice. Ferroptosis has been reported to participate in the pathogenic process of VILI. We will …
Mechanistic insights into xanthomicrol as the active anti-HCC ingredient of Phytolacca acinosa Roxb.: a network pharmacology analysis and transcriptomics …
J Liu, Y Zhou, P Zhou, T He, P Liu, J Wang, P Lin… - Journal of …, 2024 - Elsevier
Abstract Ethnopharmacological relevance Phytolacca acinosa Roxb.(PAR) is a Traditional
Chinese Medicinal (TCM) plant with a broad global distribution encompassing 35 species …
Chinese Medicinal (TCM) plant with a broad global distribution encompassing 35 species …
Ent-kaurane diterpenoids from Isodon japonica var. glaucocalyx with PCSK9 inhibitory activities
G Wang, T Chen, PJ Guo, S Peng, WQ Wang… - Phytochemistry …, 2023 - Elsevier
Three new (glaucocalyxin L− N, 1− 3) and six known ent-kauranoids (4− 9) were isolated
from the aerial part of Isodon japonica var. glaucocalyx. Compounds 1 and 2 are ent …
from the aerial part of Isodon japonica var. glaucocalyx. Compounds 1 and 2 are ent …
Antipyretic effects of Xiangqin Jiere granules on febrile young rats revealed by combining pharmacodynamics, metabolomics, network pharmacology, molecular …
X He, J Cui, H Li, Y Zhou, X Wu, C Jiang… - Journal of …, 2024 - Taylor & Francis
Xiangqin Jiere granules (XQJRG) is a proprietary Chinese medicine treating children's colds
and fevers, but its mechanism of action is unclear. The aim of this study was to explore the …
and fevers, but its mechanism of action is unclear. The aim of this study was to explore the …
A novel approach combining network pharmacology and experimental validation to study the protective effect of ginsenoside Rb1 against cantharidin‐induced …
L Xiong, K Lin, T He, X Liu, R Yuan… - Basic & Clinical …, 2024 - Wiley Online Library
Cantharidin (CTD) is a widely used anticancer compound, but its clinical use is mainly
limited due to hepatotoxicity. Ginsenoside Rb1 (GRb1) shows potential hepatoprotective …
limited due to hepatotoxicity. Ginsenoside Rb1 (GRb1) shows potential hepatoprotective …
Dimeric ent-kauranoids isolated from Isodon japonica var. Glaucocalyx and their anti-inflammatory activities
G Wang, AX Ding, GQ Qin, T Chen, XG Hu, L Zheng… - Fitoterapia, 2024 - Elsevier
The phytochemical investigation of the aerial parts of Isodon japonica var. glaucocalyx
afforded four undescribed (glaucocalyxin OR, 1–4) and six known ent-kauranoids (5–10) …
afforded four undescribed (glaucocalyxin OR, 1–4) and six known ent-kauranoids (5–10) …