[HTML][HTML] Dysregulation of Non-Coding RNAs: Roles of miRNAs and lncRNAs in the Pathogenesis of Multiple Myeloma

NH Ismail, A Mussa, MJ Al-Khreisat… - Non-coding RNA, 2023 - mdpi.com
The dysregulation of non-coding RNAs (ncRNAs), specifically microRNAs (miRNAs) and
long non-coding RNAs (lncRNAs), leads to the development and advancement of multiple …

Recent advance of small-molecule drugs for clinical treatment of multiple myeloma

JH Zhao, QL Xu, S Ma, CY Li, HC Zhang… - European Journal of …, 2023 - Elsevier
Multiple myeloma (MM) is a hematologic neoplasm of plasma cells that is currently deemed
incurable. Despite the introduction of novel immunomodulators and proteasome inhibitors …

Tumor-associated macrophages in multiple myeloma: key role in disease biology and potential therapeutic implications

E Cencini, A Sicuranza, S Ciofini, A Fabbri, M Bocchia… - Current …, 2023 - mdpi.com
Multiple myeloma (MM) is characterized by multiple relapse and, despite the introduction of
novel therapies, the disease becomes ultimately drug-resistant. The tumor …

[HTML][HTML] Plasmablastic Lymphoma. A State-of-the-Art Review: Part 1-Epidemiology, Pathogenesis, Clinicopathologic Characteristics, Differential Diagnosis, Prognostic …

M Bibas - Mediterranean Journal of Hematology and Infectious …, 2024 - ncbi.nlm.nih.gov
This two-part review aims to present a current and comprehensive understanding of the
diagnosis and management of plasmablastic lymphoma. The first section, as presented in …

A novel T cell-redirecting anti-GPRC5D× CD3 bispecific antibody with potent antitumor activity in multiple myeloma preclinical models

U Tomita, Y Ishimoto, M Ri, Y Kawase, Y Hizukuri… - Scientific Reports, 2024 - nature.com
G-protein-coupled receptor class 5 member D (GPRC5D) is detected in malignant plasma
cells in approximately 90% of patients diagnosed with multiple myeloma (MM). Here, we …

Association of proton pump inhibitor use with survival and adverse effects outcomes in patients with multiple myeloma: pooled analysis of three clinical trials

SA Almansour, MAY Alqudah, Z Abuhelwa… - Scientific Reports, 2024 - nature.com
Proton pump inhibitors (PPIs) are commonly used in cancer patients, but their impact on
treatment outcomes in multiple myeloma (MM) patients remains unclear. This study …

Beyond Chemoimmunotherapy in Advanced Non–Small Cell Lung Cancer: New Frontiers, New Challenges

G Mountzios, J Naidoo, C Wang, BC Creelan… - American Society of …, 2024 - ascopubs.org
Chemoimmunotherapy is currently the preferred first-line treatment option for the majority of
patients with advanced non–small cell lung cancer without driver genetic alterations. Most of …

An Open-Label Phase I Study of Metformin and Nelfinavir in Combination With Bortezomib in Patients With Relapsed and Refractory Multiple Myeloma

I Alodhaibi, S Ailawadhi, GP Burbano… - … Myeloma and Leukemia, 2024 - Elsevier
Background In preclinical models, combining a GLUT4 inhibitor with an oxidative
phosphorylation inhibitor shows synergistic therapeutic potential against multiple myeloma …

Progress and prospect of ASCT combined with CAR-T therapy in the treatment of multiple myeloma

S Yuan, Y Chen, H Liu - Therapeutic Advances in …, 2024 - journals.sagepub.com
Multiple myeloma (MM) is a hematological cancer characterized by abnormal proliferation of
plasma cells in bone marrow. In recent years, autologous stem cell transplantation (ASCT) …

Does the Simultaneous Introduction of Several Pharmaceuticals in the Post-Lenalidomide Era Translate to Better Outcomes in Relapse Refractory Multiple Myeloma …

I Petrakis, C Kontogiorgis, E Nena, S Delimpasi… - Cancers, 2023 - mdpi.com
Simple Summary On rare occasions, a handful of innovative cancer drugs may successfully
go through clinical trials and manage to obtain simultaneous regulatory approvals to treat a …