[HTML][HTML] A route for investigating psoriasis: from the perspective of the pathological mechanisms and therapeutic strategies of cancer

X Wu, Y Ma, L Wang, X Qin - International Journal of Molecular Sciences, 2023 - mdpi.com
Psoriasis is an incurable skin disease that develops in about two-thirds of patients before the
age of 40 and requires lifelong treatment; its pathological mechanisms have not been fully …

Metabolic drives affecting Th17/Treg gene expression changes and differentiation: impact on immune‐microenvironment regulation

C Brescia, S Audia, A Pugliano, F Scaglione, R Iuliano… - APMIS, 2024 - Wiley Online Library
The CD4+ T‐cell population plays a vital role in the adaptive immune system by
coordinating the immune response against different pathogens. A significant transformation …

ACC1-mediated fatty acid biosynthesis intrinsically controls thymic iNKT cell development

T Kanno, K Miyako, T Endo, S Yokoyama… - International …, 2024 - academic.oup.com
To meet the energetic requirements associated with activation, proliferation, and survival, T
cells switch their metabolic signatures from energetically quiescent to activated. However …

Longitudinal Variations in Th and Treg Cells Before and After Percutaneous Coronary Intervention, and Their Intercorrelations and Prognostic Value in Acute …

X Chen, M Fang, J Hong, Y Guo - Inflammation, 2024 - Springer
T helper (Th) and regulatory T (Treg) cells regulate atherosclerosis, plaque, inflammation to
involve in acute coronary syndrome (ACS). The current study aimed to investigate the …

Resolvin D1 promotes the resolution of inflammation in the ACLF rat model by increasing the proportion of Treg cells

L Chen, Y Huang, Y Chen, J Chen… - Immunity …, 2023 - Wiley Online Library
Objective Acute‐on‐chronic liver failure (ACLF) causes organ system failures in patients and
increases the risk of mortality. One of the main predictors of ACLF development in patients is …

Fatty acid metabolism constrains Th9 cell differentiation and anti-tumor immunity via modulation of retinoic acid receptor signaling

Y Endo, T Nakajima, T Kanno, Y Ueda, K Miyako… - 2024 - researchsquare.com
Abstract T helper 9 cells (Th9) are interleukin 9 (IL-9)–producing cells that have diverse
functions ranging from anti-tumor immune responses to driving allergic inflammation. Th9 …