[HTML][HTML] Microbiota–gut–brain axis and its therapeutic applications in neurodegenerative diseases

JS Loh, WQ Mak, LKS Tan, CX Ng, HH Chan… - … and Targeted Therapy, 2024 - nature.com
The human gastrointestinal tract is populated with a diverse microbial community. The vast
genetic and metabolic potential of the gut microbiome underpins its ubiquity in nearly every …

[HTML][HTML] Parkinson's disease and gut microbiota: from clinical to mechanistic and therapeutic studies

X Zhang, B Tang, J Guo - Translational Neurodegeneration, 2023 - Springer
Parkinson's disease (PD) is one of the most prevalent neurodegenerative diseases. The
typical symptomatology of PD includes motor symptoms; however, a range of nonmotor …

Efficacy of fecal microbiota transplantation in patients with Parkinson's disease: clinical trial results from a randomized, placebo-controlled design

Y Cheng, G Tan, Q Zhu, C Wang, G Ruan, S Ying… - Gut …, 2023 - Taylor & Francis
The occurrence and development of Parkinson's disease (PD) have been demonstrated to
be related to gut dysbiosis, however, the impact of fecal microbiota transplantation (FMT) on …

[HTML][HTML] Therapies for Parkinson's disease and the gut microbiome: evidence for bidirectional connection

G Hey, N Nair, E Klann, A Gurrala… - Frontiers in Aging …, 2023 - frontiersin.org
The gut brain axis (GBA), a bidirectional communication pathway has often been linked to
health and disease, and gut microbiota (GM), a key component of this pathway shown to be …

[HTML][HTML] Gut-brain axis: gut dysbiosis and psychiatric disorders in Alzheimer's and Parkinson's disease

CR Denman, SM Park, J Jo - Frontiers in Neuroscience, 2023 - frontiersin.org
Gut dysbiosis and psychiatric symptoms are common early manifestations of Alzheimer's
disease (AD) and Parkinson's disease (PD). These diseases, characterised by progressive …

[HTML][HTML] The gastrointestinal tract and Parkinson's disease

AS Higinbotham, CW Kilbane - Frontiers in cellular and infection …, 2024 - frontiersin.org
Parkinson's disease (PD) is the second most common (De Lau and Breteler, 2006) and the
most rapidly rising neurodegenerative disease in the world (GBD 2016 Parkinson's disease …

Safety and feasibility of faecal microbiota transplantation for patients with Parkinson's disease: a protocol for a self-controlled interventional donor-FMT pilot study

KEW Vendrik, VO Chernova, EJ Kuijper, EM Terveer… - BMJ open, 2023 - bmjopen.bmj.com
Introduction Experimental studies suggest a role of gut microbiota in the pathophysiology of
Parkinson's disease (PD) via the gut–brain axis. The gut microbiota can also influence the …

The use of faecal microbiota transplant as treatment for recurrent or refractory Clostridioides difficile infection and other potential indications: of joint British Society of …

BH Mullish, B Merrick, MN Quraishi, A Bak… - Journal of Hospital …, 2024 - Elsevier
Summary The first British Society of Gastroenterology (BSG) and Healthcare Infection
Society (HIS)-endorsed faecal microbiota transplant (FMT) guidelines were published in …

[HTML][HTML] Gut microbiota in perioperative neurocognitive disorders: current evidence and future directions

Y Sun, K Wang, W Zhao - Frontiers in Immunology, 2023 - frontiersin.org
Perioperative neurocognitive disorders (PND) is a common surgical anesthesia
complication characterized by impairment of memory, attention, language understanding …

The gut-brain axis in Parkinson's disease

B Bonaz - Revue Neurologique, 2023 - Elsevier
There is a bi-directional communication between the gut, including the microbiota, and the
brain through the autonomic nervous system. Accumulating evidence has suggested a …