Synopsis Carboplatin is a 'second-generation'platinum compound advocated for use in the
treatment of patients with ovarian cancer and it has also shown promise in small cell lung …

The frequency, risk factors, pathophysiology, diagnosis, and management of lung cancer are
reviewed. An estimated 157,400 Americans died of lung cancer in 2001. Lung cancer is the …

To examine whether weight loss at presentation influences outcome in patients who
received chemotherapy for lung cancer or mesothelioma. Multivariate analysis of …

PURPOSE To identify the major sites of platinum accumulation within neural tissues after
treatment with cisplatin and to determine the relationship between cumulative dosage, time …

PURPOSE The study was undertaken to define the relationship between tumor response
and carboplatin area under the curve (AUC) in patients with ovarian cancer; to study the …

Purpose To assess the efficacy and toxicity of carboplatin, etoposide, and the bcl-2
antisense oligonucleotide oblimersen as initial therapy for extensive-stage small-cell lung …

Etoposide is a podophyllotoxin derivative which delays progression of the cell cycle through
the late S or early G 2 phase. In vitro antitumour activity is dose and administration schedule …

Background. Central nervous system (CNS) germinomas respond readily to both
radiotherapy and chemotherapy. This study was designed to selectively reduce the dose of …

Impacting the lives of millions throughout the globe, cancer is the world's leading cause of
death. In cancer treatment and prognosis, a number of anticancer medicines have been …

Small cell lung cancer (SCLC) is a phenotypically heterogeneous disease with an extremely
poor prognosis, which is mainly attributed to the rapid development of resistance to …