SARS-CoV-2 non-structural proteins and their roles in host immune evasion

ZY Low, NZ Zabidi, AJW Yip, A Puniyamurti, VTK Chow… - Viruses, 2022 - mdpi.com
Coronavirus disease 2019 (COVID-19) has caused an unprecedented global crisis and
continues to threaten public health. The etiological agent of this devastating pandemic …

[HTML][HTML] Immunology of SARS-CoV-2 infection and vaccination

B Lin, L Cheng, J Zhang, M Yang, Y Zhang, J Liu… - Clinica Chimica …, 2023 - Elsevier
Comprehensive elucidation of humoral immune responses to severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection and vaccination is critical for …

Predictors of humoral response to mRNA COVID19 vaccines in kidney transplant recipients: a longitudinal study—the COViNEPH Project

A Dębska-Ślizień, Z Ślizień, M Muchlado, A Kubanek… - Vaccines, 2021 - mdpi.com
Background: The efficacy of SARS-CoV-2 vaccination among kidney transplant recipients
(KTR) is low. The main goal of this study was to analyze factors that may influence the …

SARS-CoV-2 ORF3a Protein as a Therapeutic Target against COVID-19 and Long-Term Post-Infection Effects

J Zhang, K Hom, C Zhang, M Nasr, V Gerzanich… - Pathogens, 2024 - mdpi.com
The COVID-19 pandemic caused by SARS-CoV-2 has posed unparalleled challenges due
to its rapid transmission, ability to mutate, high mortality and morbidity, and enduring health …

Antibody profiling in COVID-19 patients with different severities by using spike variant protein microarrays

WY Su, PX Du, HM Santos, TS Ho, BB Keskin… - Analytical …, 2022 - ACS Publications
The disease progression of COVID-19 varies from mild to severe, even death. However, the
link between COVID-19 severities and humoral immune specificities is not clear. Here, we …

Humoral immune response profile of COVID-19 reveals severity and variant-specific epitopes: Lessons from SARS-CoV-2 peptide microarray

A Acharjee, A Ray, A Salkar, S Bihani, C Tuckley… - Viruses, 2023 - mdpi.com
The amaranthine scale of the COVID-19 pandemic and unpredictable disease severity is of
grave concern. Serological diagnostic aids are an excellent choice for clinicians for rapid …

Mapping human norovirus antigens during infection reveals the breadth of the humoral immune response

L Su, W Huang, FH Neill, MK Estes, RL Atmar… - npj Vaccines, 2023 - nature.com
Human noroviruses (HuNoV) are the leading cause of acute gastroenteritis worldwide. The
humoral immune response plays an important role in clearing HuNoV infections and …

Antibody isotype epitope mapping of SARS‐CoV‐2 Spike RBD protein: Targets for COVID‐19 symptomatology and disease control

M Contreras, J Vicente, JJ Cerón… - European Journal of …, 2023 - Wiley Online Library
Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) still poses a challenge for
biomedicine and public health. To advance the development of effective diagnostic …

Differential Severe Acute Respiratory Syndrome Coronavirus 2–Specific Humoral Response in Inactivated Virus–Vaccinated, Convalescent, and Breakthrough …

LF Duarte, Y Vázquez… - The Journal of …, 2023 - academic.oup.com
Background We sought to identify potential antigens for discerning between humoral
responses elicited after vaccination with CoronaVac (a severe acute respiratory syndrome …

Computational design of candidate multi-epitope vaccine against SARS-CoV-2 targeting structural (S and N) and non-structural (NSP3 and NSP12) proteins

Z Ali, JV Cardoza, S Basak, U Narsaria… - Journal of …, 2023 - Taylor & Francis
The COVID-19 pandemic caused by SARS-CoV-2 virus has created a global damage and
has exposed the vulnerable side of scientific research towards novel diseases. The intensity …