Moyamoya disease is a rare cause of stroke, radiologically characterised by progressive
stenosis of the terminal portion of the internal carotid arteries and compensatory capillary …

ISG15 is an interferon-stimulated, ubiquitin-like protein that can conjugate to substrate
proteins (ISGylation) to counteract microbial infection, but the underlying mechanisms …

Systemic vascular involvement in children with cerebral arteriopathies is increasingly
recognized and often highly morbid. Fibromuscular dysplasia (FMD) represents a cerebral …

Background and Purpose: Luminal imaging (degree of stenosis) currently serves as the gold
standard to predict stroke recurrence and guide therapeutic strategies in patients with …

Paediatric arterial ischaemic stroke is an important cause of neurological morbidity in
children, with consequences including motor disorders, intellectual impairment, and …

We would like to comment on twig-like middle cerebral artery (MCA) in relation to the
interesting article “Hemorrhagic events associated with unfused or twig-like configuration of …

Background The RNF213 (ring finger protein 213 gene) variant R4810K is a susceptibility
allele not only for Moyamoya disease (MMD) but also for intracranial atherosclerosis (ICAS) …

The genetic background of intracranial artery stenosis (ICAS), a major cause of ischemic
stroke, remains elusive. We performed the world's first genome-wide association study …

Background and Objectives Intracranial artery stenosis is the predominant etiology of
ischemic stroke in the Asian population. Furthermore, the presence of the RNF213 p …

Moyamoya disease (MMD) is an idiopathic cerebrovascular disease which was first
described by Suzuki and Takaku in 1969. Moyamoya disease is a non-atherosclerotic …