[HTML][HTML] SARS-CoV-2 viral load and shedding kinetics
SARS-CoV-2 viral load and detection of infectious virus in the respiratory tract are the two
key parameters for estimating infectiousness. As shedding of infectious virus is required for …
key parameters for estimating infectiousness. As shedding of infectious virus is required for …
COVID-19 vaccines in patients with cancer: immunogenicity, efficacy and safety
A Fendler, EGE de Vries… - Nature Reviews …, 2022 - nature.com
Patients with cancer have a higher risk of severe coronavirus disease (COVID-19) and
associated mortality than the general population. Owing to this increased risk, patients with …
associated mortality than the general population. Owing to this increased risk, patients with …
SARS-CoV-2 infection and persistence in the human body and brain at autopsy
Abstract Coronavirus disease 2019 (COVID-19) is known to cause multi-organ dysfunction,–
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
during acute infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
[HTML][HTML] Infectious viral load in unvaccinated and vaccinated individuals infected with ancestral, Delta or Omicron SARS-CoV-2
O Puhach, K Adea, N Hulo, P Sattonnet, C Genecand… - Nature medicine, 2022 - nature.com
Infectious viral load (VL) expelled as droplets and aerosols by infected individuals partly
determines transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
determines transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
[HTML][HTML] Inflammasome activation in infected macrophages drives COVID-19 pathology
Severe COVID-19 is characterized by persistent lung inflammation, inflammatory cytokine
production, viral RNA and a sustained interferon (IFN) response, all of which are …
production, viral RNA and a sustained interferon (IFN) response, all of which are …
A phase 2a clinical trial of molnupiravir in patients with COVID-19 shows accelerated SARS-CoV-2 RNA clearance and elimination of infectious virus
There is an urgent need for an effective, oral, direct-acting therapeutic to block transmission
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …
SARS-CoV-2 variants of concern partially escape humoral but not T cell responses in COVID-19 convalescent donors and vaccine recipients
D Geers, MC Shamier, S Bogers, G den Hartog… - Science …, 2021 - science.org
The emergence of SARS-CoV-2 variants harboring mutations in the spike (S) protein has
raised concern about potential immune escape. Here, we studied humoral and cellular …
raised concern about potential immune escape. Here, we studied humoral and cellular …
Estimating infectiousness throughout SARS-CoV-2 infection course
INTRODUCTION Although post facto studies have revealed the importance of severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from presymptomatic …
respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission from presymptomatic …
[HTML][HTML] Post-acute COVID-19 syndrome
A Nalbandian, K Sehgal, A Gupta, MV Madhavan… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the pathogen
responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in …
responsible for the coronavirus disease 2019 (COVID-19) pandemic, which has resulted in …
[HTML][HTML] Efficacy of ChAdOx1 nCoV-19 (AZD1222) vaccine against SARS-CoV-2 variant of concern 202012/01 (B. 1.1. 7): an exploratory analysis of a randomised …
Background A new variant of SARS-CoV-2, B. 1.1. 7, emerged as the dominant cause of
COVID-19 disease in the UK from November, 2020. We report a post-hoc analysis of the …
COVID-19 disease in the UK from November, 2020. We report a post-hoc analysis of the …