Mucoadhesive carriers for oral drug delivery

R Kumar, T Islam, M Nurunnabi - Journal of Controlled Release, 2022 - Elsevier
Among the various dosage forms, oral medicine has extensive benefits including ease of
administration and patients' compliance, over injectable, suppositories, ocular and nasal …

Diagnosis of Helicobacter pylori Using Invasive and Noninvasive Approaches

A Talebi Bezmin Abadi - Journal of pathogens, 2018 - Wiley Online Library
Helicobacter pylori (H. pylori) as gram‐negative and spiral microorganism is responsible for
colonization in the gastric microniche for more than 50% of world population. Recent studies …

Expression of the potential therapeutic target claudin-18.2 is frequently decreased in gastric cancer: results from a large Caucasian cohort study

M Dottermusch, S Krüger, HM Behrens, C Halske… - Virchows Archiv, 2019 - Springer
Gastric cancer (GC) is frequently diagnosed and treated in advanced tumour stages with
poor prognosis. Recent studies have identified isoform 2 of the tight junction protein claudin …

[HTML][HTML] Long non-coding RNA PTENP1 functions as a ceRNA to modulate PTEN level by decoying miR-106b and miR-93 in gastric cancer

R Zhang, Y Guo, Z Ma, G Ma, Q Xue, F Li, L Liu - Oncotarget, 2017 - ncbi.nlm.nih.gov
Recent studies have shown that competing endogenous RNAs (ceRNAs) play an important
role in the regulation of gene expression, and participate in a wide range of biological …

BCAT1 activates PI3K/AKT/mTOR pathway and contributes to the angiogenesis and tumorigenicity of gastric cancer

X Shu, PP Zhan, LX Sun, L Yu, J Liu, LC Sun… - Frontiers in Cell and …, 2021 - frontiersin.org
Background Focusing on antiangiogenesis may provide promising choices for treatment of
gastric cancer (GC). This study aimed to investigate the mechanistic role of BCAT1 in the …

Baicalein enhanced cisplatin sensitivity of gastric cancer cells by inducing cell apoptosis and autophagy via Akt/mTOR and Nrf2/Keap 1 pathway

P Li, J Hu, B Shi, J Tie - Biochemical and Biophysical Research …, 2020 - Elsevier
Baicalein is a natural flavonoid with various pharmacological activities including antitumor.
The synergistic anti-cancer effect of the combination of baicalein and Cisplatin (DDP) on …

Adapting and surviving: intra and extra-cellular remodeling in drug-resistant gastric cancer cells

S Russi, HK Verma, S Laurino, P Mazzone… - International journal of …, 2019 - mdpi.com
Despite the significant recent advances in clinical practice, gastric cancer (GC) represents a
leading cause of cancer-related deaths in the world. In fact, occurrence of chemo-resistance …

Epigenetic mechanisms in gastric cancer: potential new therapeutic opportunities

M Canale, A Casadei-Gardini, P Ulivi… - International Journal of …, 2020 - mdpi.com
Gastric cancer (GC) is one of the deadliest malignancies worldwide. Complex disease
heterogeneity, late diagnosis, and suboptimal therapies result in the poor prognosis of …

Antibody drug conjugates in gastrointestinal cancer: From lab to clinical development

D Singh, D Dheer, A Samykutty, R Shankar - Journal of Controlled Release, 2021 - Elsevier
The antibody-drug conjugates (ADCs) are one the fastest growing biotherapeutics in
oncology and are still in their infancy in gastrointestinal (GI) cancer for clinical applications to …

Bruceine D inhibits cell proliferation through downregulating LINC01667/MicroRNA-138-5p/Cyclin E1 axis in gastric cancer

L Li, Z Dong, P Shi, L Tan, J Xu, P Huang… - Frontiers in …, 2020 - frontiersin.org
Objective: Gastric cancer is one of the most common malignant tumors. Bruceine D (BD) is
one of the extracts of Brucea javanica. In recent years, it has been reported that BD has anti …