Engineered nanomedicines with enhanced tumor penetration

J Ding, J Chen, L Gao, Z Jiang, Y Zhang, M Li, Q Xiao… - Nano Today, 2019 - Elsevier
Nanomedicine has been extensively explored to enhance the efficacy of chemotherapy with
modest therapeutic efficacy in the clinic, owing to various factors. A primary factor is …

Tailoring gelation mechanisms for advanced hydrogel applications

V Nele, JP Wojciechowski… - Advanced Functional …, 2020 - Wiley Online Library
Hydrogels are one of the most commonly explored classes of biomaterials. Their chemical
and structural versatility has enabled their use across a wide range of applications, including …

Micro/nanoparticle‐augmented sonodynamic therapy (SDT): breaking the depth shallow of photoactivation

X Qian, Y Zheng, Y Chen - Advanced materials, 2016 - Wiley Online Library
The fast development of photoactivation for cancer treatment provides an efficient photo‐
therapeutic strategy for cancer treatment, but traditional photodynamic or photothermal …

Noninvasive imaging of nanomedicines and nanotheranostics: principles, progress, and prospects

S Kunjachan, J Ehling, G Storm, F Kiessling… - Chemical …, 2015 - ACS Publications
Nanomedicine is defined as “the application of nanotechnology to medicine, including the
use of nanometer-sized carrier materials for facilitating disease diagnosis, disease treatment …

[HTML][HTML] Hyperthermia and smart drug delivery systems for solid tumor therapy

ALB Seynhaeve, M Amin, D Haemmerich… - Advanced Drug Delivery …, 2020 - Elsevier
Chemotherapy is a cornerstone of cancer therapy. Irrespective of the administered drug, it is
crucial that adequate drug amounts reach all cancer cells. To achieve this, drugs first need …

Sonodynamic therapy (SDT): a novel strategy for cancer nanotheranostics

X Pan, H Wang, S Wang, X Sun, L Wang… - Science China Life …, 2018 - Springer
Sonodynamic therapy (SDT) is a promising non-invasive therapeutic modality. Compared to
photo-inspired therapy, SDT provides many opportunities and benefits, including deeper …

Drug delivery strategies for platinum-based chemotherapy

RJ Browning, PJT Reardon, M Parhizkar, RB Pedley… - ACS …, 2017 - ACS Publications
Few chemotherapeutics have had such an impact on cancer management as cis-
diamminedichloridoplatinum (II)(CDDP), also known as cisplatin. The first member of the …

Recent progress in development of new sonosensitizers for sonodynamic cancer therapy

H Chen, X Zhou, Y Gao, B Zheng, F Tang, J Huang - Drug discovery today, 2014 - Elsevier
Highlights•Photodynamic therapy (PDT) suffers from the major shortcoming derived from the
limited penetrability of visible light.•Sonodynamic therapy (SDT) is deemed to overcome the …

[HTML][HTML] Temperature-sensitive polymers to promote heat-triggered drug release from liposomes: Towards bypassing EPR

M Amin, T Lammers, TLM Ten Hagen - Advanced Drug Delivery Reviews, 2022 - Elsevier
Heat-triggered drug release from temperature-sensitive nanocarriers upon the application of
mild hyperthermia is a promising approach to achieve site-specific delivery of drugs. The …

Ultrasound‐propelled nanocups for drug delivery

JJ Kwan, R Myers, CM Coviello, SM Graham, AR Shah… - small, 2015 - Wiley Online Library
Ultrasound‐induced bubble activity (cavitation) has been recently shown to actively
transport and improve the distribution of therapeutic agents in tumors. However, existing …