Unraveling a Unique Metastable Phase of a Proxyphylline Cocrystal Exclusively Produced by Compressed Carbon Dioxide

F Ercicek, M Marchivie, L Nimod, H Cercel… - Crystal Growth & …, 2024 - ACS Publications
In this work, racemic proxyphylline ((±)-PXL, a chiral drug) was cocrystallized for the first time
with 4-hydroxybenzoic acid (4-HBA) from three solvents (acetone, ethyl acetate, and …

[HTML][HTML] Predicting particle quality attributes of organic crystalline materials using particle informatics

E Prandini, E Calì, AGP Maloney, E Parisi, E Simone - Powder Technology, 2024 - Elsevier
In this work, a novel type of quercetin solvate of dimethylformamide (QDMF) was studied.
The crystal structure was solved using single crystal X-ray diffraction and analysed using …

Cocrystal of Naringenin and Norfloxacin: Crystal Transformation, Solubility, and Antibacterial and Anticancer Activities

X Zeng, C Zheng, S Qiu, X Jiang, X Wang… - Crystal Growth & …, 2024 - ACS Publications
Drug cocrystals can modulate the physical and chemical properties of drugs, even
complement each other's strengths, and have a synergistic enhancement effect. Here, we …

Synthesis of naringenin-betaine cocrystal by gas antisolvent technique and cell models for in vitro permeation studies

PV Oliveira, GPS Aguiar, AM Siebel, LG Müller… - Journal of Drug Delivery …, 2024 - Elsevier
Naringenin (NRG) is a flavanone characterized by potential neuroprotective properties, even
if low water solubility and poor oral bioavailability limit the ability of this compound to target …

Multicomponent Crystals of Famotidine and Trimethoprim as Improved Pharmaceutical Materials: Design, Characterization, and Properties

TY Zeleke - 2023 - agnee.tezu.ernet.in
ABSTRACT This thesis entitled “Multicomponent Crystals of Famotidine and Trimethoprim
as Improved Pharmaceutical Materials: Design, Characterization, and Properties” consists of …