Long COVID (LC) is a condition in which patients do not fully recover from the initial SARS-
CoV-2 infection but rather have persistent or new symptoms for months to years following …

Since the onset of the COVID-19 pandemic, significant progress has been made in
developing effective preventive and therapeutic strategies against severe acute SARS-CoV …

Early stages of deadly respiratory diseases including COVID-19 are challenging to elucidate
in humans. Here, we define cellular tropism and transcriptomic effects of SARS-CoV-2 virus …

Despite tremendous progress in the development of mature heart-on-a-chip models, human
cell–based models of myocardial inflammation are lacking. Here, we bioengineered a …

It has been proposed that coronavirus nsp15 mediates evasion of host cell double-stranded
(ds) RNA sensors via its uracil-specific endoribonuclease activity. However, how nsp15 …

ABSTRACT HLA-E expression plays a central role for modulation of NK cell function by
interaction with inhibitory NKG2A and stimulatory NKG2C receptors on canonical and …

Innate lymphocytes (ILCs) rapidly respond to and protect against invading pathogens and
cancer. ILCs include natural killer (NK) cells, ILC1s, ILC2s, ILC3s, and lymphoid tissue …

Introduction It is now clear that coronavirus disease 19 (COVID-19) severity is associated
with a dysregulated immune response, but the relative contributions of different immune …

Many pathogens enter the host through mucosal sites. Thus, interfering with pathogen entry
through local neutralization at mucosal sites therefore is an effective strategy for preventing …

SARS-CoV-2 has been the subject of extensive research. Through substantial efforts,
researchers have tracked the virus's variants and developed vaccines, diagnostic tests, and …