Higher risk for hematological malignancies in inflammatory bowel disease: a nationwide population-based study in Taiwan

LH Wang, YJ Yang, WC Cheng, WM Wang… - Official journal of the …, 2016 - journals.lww.com
Objectives: The relationship between inflammatory bowel disease (IBD) and cancer remains
unclear especially in Asian populations. Therefore, we conducted a nationwide population …

Biologic use patterns and predictors for non-persistence and switching of biologics in patients with inflammatory bowel disease: a nationwide population-based study

YS Jung, M Han, S Park, JH Cheon - Digestive diseases and sciences, 2020 - Springer
Background Data on real-life patterns of biologic use for inflammatory bowel disease (IBD)
are scarce. Aims We aimed to examine the patterns of biologic use and the factors …

Genetics of inflammatory bowel diseases: A comparison between W estern and E astern perspectives

JH Cheon - Journal of gastroenterology and hepatology, 2013 - Wiley Online Library
Inflammatory bowel disease (IBD) is a chronic relapsing intestinal inflammatory disorder with
unidentified causes. Currently, studies indicate that IBD results from a complex interplay …

Inflammatory bowel diseases among immigrants from low-to high-incidence countries: opportunities and considerations

M Agrawal, J Burisch, JF Colombel… - Journal of Crohn's and …, 2020 - academic.oup.com
The inflammatory bowel diseases [IBDs], inclusive of Crohn's disease [CD] and ulcerative
colitis [UC], are chronic, progressive immune-mediated diseases associated with high …

[HTML][HTML] Efficacy and safety of vedolizumab in Crohn's disease in patients from Asian countries in the GEMINI 2 study

R Banerjee, SW Chuah, IN Hilmi, DC Wu… - Intestinal …, 2021 - ncbi.nlm.nih.gov
Methods During the induction phase (doses at day 1, 15), clinical remission, enhanced
clinical response, and change in C-reactive protein at 6 weeks; during the maintenance …

Efficacy and safety of adalimumab in Chinese patients with moderately to severely active Crohn's disease: results from a randomized trial

B Chen, X Gao, J Zhong, J Ren, X Zhu… - Therapeutic …, 2020 - journals.sagepub.com
Background and Aims: Efficacy of adalimumab in Crohn's disease (CD) has not been shown
in China. The aim of this study was to evaluate the efficacy and safety of adalimumab in …

[HTML][HTML] Gastrointestinal disorders and intestinal bacteria: advances in research and applications in therapy

T Ohkusa, Y Nishikawa, N Sato - Frontiers in Medicine, 2023 - frontiersin.org
Intestinal bacteria coexist with humans and play a role in suppressing the invasion of
pathogens, producing short-chain fatty acids, producing vitamins, and controlling the …

[HTML][HTML] Immunotherapy in patients with autoimmune disease

S Rakshit, JR Molina - Journal of Thoracic Disease, 2020 - ncbi.nlm.nih.gov
Immune checkpoint inhibitors (ICIs) such as cytotoxic T-lymphocyte-associated protein 4
(CTLA-4), programmed cell death protein 1 (PD-1) and programmed cell death protein …

[HTML][HTML] Association between variants of the autophagy related gene–IRGM and susceptibility to Crohn's disease and ulcerative colitis: a meta-analysis

XC Lu, Y Tao, C Wu, PL Zhao, K Li, JY Zheng, LX Li - PloS one, 2013 - journals.plos.org
Background Polymorphisms in immunity-related GTPase family M (IRGM) gene may be
associated with inflammatory bowel disease (IBD) by affecting autophagy. However, the …

The phenotypic spectrum of new-onset IBD in Canadian children of South Asian ethnicity: a prospective multi-centre comparative study

J Dhaliwal, MW Carroll, JC Debruyn… - Journal of Crohn's …, 2022 - academic.oup.com
Background Canadian-born children of South Asian [SA] ethnicity develop inflammatory
bowel disease [IBD] at similar rates to those among Caucasian children. We evaluated the …