Chronic caloric restriction (CR) has powerful anticarcinogenic actions in both preclinical and
clinical studies but may be difficult to sustain. As an alternative to CR, there has been …

Time-restricted feeding (TRF, animal-based studies) and time-restricted eating (TRE,
humans) are an emerging behavioral intervention approach based on the understanding of …

Time-restricted feeding (TRF) improves metabolic health. Both early TRF (eTRF, food intake
restricted to the early part of the day) and mid-day TRF (mTRF, food intake restricted to the …

Importance The efficacy and safety of time-restricted eating have not been explored in large
randomized clinical trials. Objective To determine the effect of 16: 8-hour time-restricted …

Importance It is unclear how effective intermittent fasting is for losing weight and body fat,
and the effects may depend on the timing of the eating window. This randomized trial …

Intermittent fasting appears an equivalent alternative to calorie restriction (CR) to improve
health in humans. However, few trials have considered applying meal timing during the …

Autophagy, an essential cellular process that mediates degradation of proteins and
organelles in lysosomes, has been tightly linked to cellular quality control for its role as part …

Diet modification and exercise training are primary lifestyle strategies for obesity
management, but poor adherence rates limit their effectiveness. Time-restricted eating (TRE) …

As years progress, we are found more often in a postprandial than a postabsorptive state.
Chrononutrition is an integral part of metabolism, pancreatic function, and hormone …

Objective In contrast to intentionally restricting energy intake, restricting the eating window
may be an option for treating obesity. By comparing time‐restricted eating (TRE) with an …