[HTML][HTML] Molecular pathways involved in COVID-19 and potential pathway-based therapeutic targets

M Farahani, Z Niknam, LM Amirabad… - Biomedicine & …, 2022 - Elsevier
Deciphering the molecular downstream consequences of severe acute respiratory
syndrome coronavirus (SARS-CoV)− 2 infection is important for a greater understanding of …

Structural and non-structural proteins in SARS-CoV-2: potential aspects to COVID-19 treatment or prevention of progression of related diseases

S Kakavandi, I Zare, M VaezJalali, M Dadashi… - Cell Communication and …, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is caused by a new member of the
Coronaviridae family known as severe acute respiratory syndrome coronavirus 2 (SARS …

Understanding the role of ACE-2 receptor in pathogenesis of COVID-19 disease: a potential approach for therapeutic intervention

E Shirbhate, J Pandey, VK Patel, M Kamal… - Pharmacological …, 2021 - Springer
Angiotensin-converting enzyme (ACE) and its homologue, ACE2, are commonly allied with
hypertension, renin–angiotensin–aldosterone system pathway, and other cardiovascular …

Acute and post-acute phase of COVID-19: analyzing expression patterns of miRNA-29a-3p, 146a-3p, 155-5p, and let-7b-3p in PBMC

T Donyavi, F Bokharaei-Salim, HB Baghi… - International …, 2021 - Elsevier
Background When a new pathogen, such as severe acute respiratory syndrome coronavirus
2, appears all novel information can aid in the process of monitoring and in the diagnosis of …

Viral coinfections in COVID‐19

PS Aghbash, N Eslami, M Shirvaliloo… - Journal of Medical …, 2021 - Wiley Online Library
The most consequential challenge raised by coinfection is perhaps the inappropriate
generation of recombinant viruses through the exchange of genetic material among different …

Kinases as potential therapeutic targets for anti-coronaviral therapy

T Pillaiyar, S Laufer - Journal of Medicinal Chemistry, 2021 - ACS Publications
The global coronavirus disease-19 (COVID-19) has affected more than 140 million and
killed more than 3 million people worldwide as of April 20, 2021. The novel human severe …

An inhaled bioadhesive hydrogel to shield non-human primates from SARS-CoV-2 infection

X Mei, J Li, Z Wang, D Zhu, K Huang, S Hu… - Nature materials, 2023 - nature.com
The surge of fast-spreading SARS-CoV-2 mutated variants highlights the need for fast,
broad-spectrum strategies to counteract viral infections. In this work, we report a physical …

[PDF][PDF] Role of miR-2392 in driving SARS-CoV-2 infection

JT McDonald, FJ Enguita, D Taylor, RJ Griffin, W Priebe… - Cell reports, 2021 - cell.com
MicroRNAs (miRNAs) are small non-coding RNAs involved in post-transcriptional gene
regulation that have a major impact on many diseases and provide an exciting avenue …

Covid-19 and development of heart failure: mystery and truth

H Onohuean, HM Al-Kuraishy, AI Al-Gareeb… - Naunyn-Schmiedeberg's …, 2021 - Springer
Abstract Coronavirus disease 2019 (Covid-19) is a novel worldwide pandemic caused by a
novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). During Covid-19 …

p53/NF-kB balance in SARS-CoV-2 infection: From OMICs, genomics and pharmacogenomics insights to tailored therapeutic perspectives (COVIDomics)

D Milani, L Caruso, E Zauli, AM Al Owaifeer… - Frontiers in …, 2022 - frontiersin.org
SARS-CoV-2 infection affects different organs and tissues, including the upper and lower
airways, the lung, the gut, the olfactory system and the eye, which may represent one of the …