Neuroimmune crosstalk in the cornea: The role of immune cells in corneal nerve maintenance during homeostasis and inflammation

M Wu, LJ Hill, LE Downie, HR Chinnery - Progress in Retinal and Eye …, 2022 - Elsevier
In the cornea, resident immune cells are in close proximity to sensory nerves, consistent with
their important roles in the maintenance of nerves in both homeostasis and inflammation …

[HTML][HTML] Advances in dry eye disease examination techniques

Y Wu, C Wang, X Wang, Y Mou, K Yuan… - Frontiers in …, 2022 - frontiersin.org
Dry eye-related ocular surface examination is very important in the diagnosis and treatment
of dry eye disease. With the recent advances in science and technology, dry eye …

Small fiber neuropathy in the cornea of Covid-19 patients associated with the generation of ocular surface disease

A Barros, J Queiruga-Piñeiro, J Lozano-Sanroma… - The Ocular Surface, 2022 - Elsevier
Purpose To describe the association between Sars-CoV-2 infection and small fiber
neuropathy in the cornea identified by in vivo corneal confocal microscopy. Methods Twenty …

Modulating the tachykinin: Role of substance P and neurokinin receptor expression in ocular surface disorders

RB Singh, A Naderi, W Cho, G Ortiz, A Musayeva… - The ocular …, 2022 - Elsevier
Substance P (SP) is a tachykinin expressed by various cells in the nervous and immune
systems. SP is predominantly released by neurons and exerts its biological and …

Pathophysiology of dry eye disease and novel therapeutic targets

EM Messmer - Experimental Eye Research, 2022 - Elsevier
Abstract The pathophysiology of Dry Eye Disease (DED) is complex, and therapy may be a
challenge. Tear film instability, tear film hyperosmolarity, ocular surface damage and ocular …

Omega-3 polyunsaturated fatty acids and corneal nerve health: Current evidence and future directions

AC Britten-Jones, JP Craig, LE Downie - The Ocular Surface, 2023 - Elsevier
Corneal nerves play a key role in maintaining ocular surface integrity. Corneal nerve
damage, from local or systemic conditions, can lead to ocular discomfort, pain, and, if poorly …

[HTML][HTML] Neural Regeneration in Dry Eye Secondary to Systemic Lupus Erythematosus Is Also Disrupted like in Rheumatoid Arthritis, but in a Progressive Fashion

B Sonkodi, L Marsovszky, A Csorba, A Balog… - International Journal of …, 2023 - mdpi.com
Our objective in this study was to analyze the aberrant neural regeneration activity in the
cornea by means of in vivo confocal microscopy in systemic lupus erythematosus patients …

Neurostimulation for dry eye disease

N Erdinest, S Pincovich, N London… - Current Opinion in …, 2022 - journals.lww.com
Neurostimulation for dry eye disease : Current Opinion in Allergy and Clinical Immunology
Neurostimulation for dry eye disease : Current Opinion in Allergy and Clinical Immunology Log …

[HTML][HTML] Recovery of corneal innervation after treatment in dry eye disease: A confocal microscopy study

A Barros, J Lozano-Sanroma… - Journal of Clinical …, 2023 - mdpi.com
Purpose: To analyze the changes in corneal innervation by means of in vivo corneal
confocal microscopy (IVCM) in patients diagnosed with Evaporative (EDE) and Aqueous …

[HTML][HTML] Personalized management of dry eye disease: beyond artificial tears

C Matossian, M Crowley, L Periman… - Clinical Ophthalmology …, 2022 - ncbi.nlm.nih.gov
Dry eye disease (DED) is a multifactorial disease of the ocular surface that may be
accompanied by discomfort and visual disturbances to a level that reduces quality of life …