This investigation elucidates the Akt/mitochondrial ATP-sensitive K+ (mitoKATP) channel
signaling pathway in late pharmacological preconditioning, using the mitoKATP channel …

Preconditioning describes the phenomenon by which a traumatic or stressful stimulus
confers protection against subsequent injury. Originally recognized in dog heart subjected to …

Preconditioning is a phenomenon, where brief periods of stress such as ischemia, heat
shock or certain pharmacological agents make the heart tolerant to subsequent lethal …

ATP and other purine nucleotides are important biomarkers for ischemia and may have
considerable potential as targets for management of ischemic heart disease and stroke. The …

Cardiac preconditioning is mediated by protein kinase C. Although endogenous calcium is a
potent stimulus of protein kinase C, it remains unknown whether preischemic administration …

Adaptation to intermittent high altitude (IHA) hypoxia can protect the heart against ischemia-
reperfusion injury. In view of the fact that both Ca2+ paradox and ischemia-reperfusion injury …

Cardiac preconditioning describes the phenomenon by which transient ischemia induces
myocardial protection against subsequent ischemia and reperfusion injury. Ten years have …

Introduction: Oxidative stress, as exerted by free radicals within biological systems, is known
to exert numerous physiological and pathological effects on the cardiovascular system …

This review is intended to discuss the newly discovered role of preconditioning which should
make it an attractive therapeutic stimulus for repairing the injured myocardium. We recently …

Caloric restriction leads to changes in heart geometry and function although the underlying
mechanism remains elusive. Autophagy, a conserved pathway for degradation of …