Innate immunological pathways in COVID-19 pathogenesis
SR Paludan, TH Mogensen - Science immunology, 2022 - science.org
Coronavirus disease 2019 (COVID-19) is a disease characterized by a profound
dysregulation of the innate immune system. This knowledge has emerged from the large …
dysregulation of the innate immune system. This knowledge has emerged from the large …
[HTML][HTML] COVID-19 and cellular senescence
CA Schmitt, T Tchkonia, LJ Niedernhofer… - Nature Reviews …, 2023 - nature.com
The clinical severity of coronavirus disease 2019 (COVID-19) is largely determined by host
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …
factors. Recent advances point to cellular senescence, an ageing-related switch in cellular …
[HTML][HTML] Dexamethasone modulates immature neutrophils and interferon programming in severe COVID-19
Although critical for host defense, innate immune cells are also pathologic drivers of acute
respiratory distress syndrome (ARDS). Innate immune dynamics during Coronavirus …
respiratory distress syndrome (ARDS). Innate immune dynamics during Coronavirus …
Immunosuppressive reprogramming of neutrophils by lung mesenchymal cells promotes breast cancer metastasis
Neutrophils, the most abundant innate immune cells, function as crucial regulators of the
adaptive immune system in diverse pathological conditions, including metastatic cancer …
adaptive immune system in diverse pathological conditions, including metastatic cancer …
[HTML][HTML] The role of neutrophil extracellular traps in acute lung injury
Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high
morbidity and mortality. Neutrophils play a key role in the development of different forms of …
morbidity and mortality. Neutrophils play a key role in the development of different forms of …
Assessing the impact of low level laser therapy (LLLT) on biological systems: a review
Purpose: Low level laser therapy (LLLT) in the visible to near infrared spectral band (390–
1100 nm) is absorption of laser light at the electronic level, without generation of heat. It may …
1100 nm) is absorption of laser light at the electronic level, without generation of heat. It may …
[HTML][HTML] Aging, inflammaging and immunosenescence as risk factors of severe COVID-19
AM Tizazu, HM Mengist, G Demeke - Immunity & Ageing, 2022 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is a respiratory infectious disease caused
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …
by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). COVID-19 is …
[HTML][HTML] Neutrophils in COVID-19: recent insights and advances
J Li, K Zhang, ye Zhang, Z Gu, C Huang - Virology journal, 2023 - Springer
Abstract Coronavirus disease 2019 (COVID-19) is an acute respiratory disease caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to acute …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which can lead to acute …
[HTML][HTML] Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Programmed cell death: the pathways to severe COVID-19?
Two years after the emergence of SARS-CoV-2, our understanding of COVID-19 disease
pathogenesis is still incomplete. Despite unprecedented global collaborative scientific efforts …
pathogenesis is still incomplete. Despite unprecedented global collaborative scientific efforts …