SARS-CoV-2 variants, vaccines, and host immunity

P Mistry, F Barmania, J Mellet, K Peta… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new beta coronavirus
that emerged at the end of 2019 in the Hubei province of China. SARS-CoV-2 causes …

The mechanism underlying extrapulmonary complications of the coronavirus disease 2019 and its therapeutic implication

Q Ning, D Wu, X Wang, D Xi, T Chen, G Chen… - … and Targeted Therapy, 2022 - nature.com
Abstract The coronavirus disease 2019 (COVID-19) is a highly transmissible disease
caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that poses a …

Immune responses in mildly versus critically ill COVID-19 patients

H Nasrollahi, AG Talepoor, Z Saleh… - Frontiers in …, 2023 - frontiersin.org
The current coronavirus pandemic (COVID-19), caused by SARS-CoV-2, has had
devastating effects on the global health and economic system. The cellular and molecular …

IL 33 correlates with COVID-19 severity, radiographic and clinical finding

SS Markovic, M Jovanovic, N Gajovic… - Frontiers in …, 2021 - frontiersin.org
Objective: The increased level of interleukin (IL)-33 is considered as a predictor of severe
coronavirus disease 2019 (COVID-19) infection, but its role at different stages of the disease …

Glucose metabolism disorder: a potential accomplice of SARS-CoV-2

Y Luan, Y Luan, H He, B Jue, Y Yang, B Qin… - International Journal of …, 2023 - nature.com
Abstract Globally, 265,713,467 confirmed cases of SARS-CoV-2 (CoV-2), including
5,260,888 deaths, have been reported by the WHO. It is important to study the mechanism of …

[HTML][HTML] Pyroptotic cell death in SARS-CoV-2 infection: revealing its roles during the immunopathogenesis of COVID-19

M Wang, W Chang, L Zhang… - International Journal of …, 2022 - ncbi.nlm.nih.gov
The rapid dissemination of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),
the causative agent of coronavirus disease 2019 (COVID-19), remains a global public health …

NSAIDs/nitazoxanide/azithromycin repurposed for COVID-19: potential mitigation of the cytokine storm interleukin-6 amplifier via immunomodulatory effects

MT Kelleni - Expert Review of Anti-infective Therapy, 2022 - Taylor & Francis
Introduction Mediators of immunity and inflammation are playing a crucial role in COVID-19
pathogenesis and complications as demonstrated by several genetic and clinical studies …

Monocyte distribution width as a novel sepsis indicator in COVID-19 patients

L Alsuwaidi, S Al Heialy, N Shaikh, F Al Najjar… - BMC infectious …, 2022 - Springer
Background The severe acute respiratory syndrome coronavirus (SARS-CoV-2) is a highly
transmittable virus which causes the novel coronavirus disease (COVID-19). Monocyte …

Severity of SARS-CoV-2 infection is associated with high numbers of alveolar mast cells and their degranulation

O Krysko, JH Bourne, E Kondakova… - Frontiers in …, 2022 - frontiersin.org
Background The systemic inflammatory response post-SARS-CoV-2 infection increases pro-
inflammatory cytokine production, multi-organ damage, and mortality rates. Mast cells (MC) …

Age-dependent immune responses in COVID-19-mediated liver injury: focus on cytokines

N Aghamohamadi, F Shahba… - Frontiers in …, 2023 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is potentially pathogenic
and causes severe symptoms; in addition to respiratory syndromes, patients might …