The mitotic spindle-related seven-gene predicts the prognosis and immune microenvironment of lung adenocarcinoma

R Shen, Z Li, X Wu - Journal of Cancer Research and Clinical Oncology, 2023 - Springer
Purpose Abnormalities in the mitotic spindle have been linked to a variety of cancers. Data
on their role in the onset, progression, and treatment of lung adenocarcinoma (LUAD) need …

Expression and potential molecular mechanism of TOP2A in metastasis of non-small cell lung cancer

J Wu, W Li, X Zhang, F Shi, Q Jia, Y Wang, Y Shi… - Scientific Reports, 2024 - nature.com
Abstract DNA topoisomerase II alpha (TOP2A) expression, gene alterations, and enzyme
activity have been studied in various malignant tumors. Abnormal elevation of TOP2A …

Bioinformatics and system Biology approach to reveal the interaction network and the therapeutic implications for non-small cell lung cancer patients With COVID-19

Z Zhuang, X Zhong, Q Chen, H Chen… - Frontiers in …, 2022 - frontiersin.org
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the leading
cause of coronavirus disease-2019 (COVID-19), is an emerging global health crisis. Lung …

Gene polymorphism and prediction of toxicity to platinum‐based chemotherapy in patients with gynecologic cancer

X Huang, J Li, X Pang, J Zhu, J Pan… - Clinical and …, 2023 - Wiley Online Library
The relationship between single nucleotide polymorphisms (SNPs) at various loci and
adverse drug reactions (ADRs) in patients with gynecologic cancer receiving platinum …

代谢相关脂肪性肝病患者血维生素特征及疾病严重程度相关性分析.

熊波, 郑金鑫, 谢芸琦, 饶丽樱, 刘晓军… - China Tropical …, 2024 - search.ebscohost.com
目的探索代谢相关脂肪性肝病(metabolic-related fatty liver disease, MAFLD) 患者血维生素A,
B2, B6, B12, D, E, K1, K2 和叶酸的代谢异常特征及其与MAFLD 严重程度的相关性. 方法2022 …

ERCC1 and ERCC2 genes expression and their SNPs variants identify a favorable signature for SCLC patients treated with platinum-based chemotherapy

E Caliman, S Fancelli, F Scolari, A Pasqui… - 2023 - researchsquare.com
Background: Platinum chemotherapy (CT) remains the backbone of systemic therapy for
patients with small-cell lung cancer (SCLC). The nucleotide excision repair (NER) pathway …