A total of 378 novel drugs and 27 biosimilars approved by the US Food and Drug Administration (FDA) between 2010 and 2019 were evaluated according to approval …
Vaccines are effective interventions that can reduce the high burden of diseases globally. However, public vaccine hesitancy is a pressing problem for public health authorities. With …
Drug repurposing involves the identification of new applications for existing drugs at a lower cost and in a shorter time. There are different computational drug-repurposing strategies and …
Historically, plants have been sought after as bio-factories for the production of diverse chemical compounds that offer a multitude of possibilities to cure diseases. To combat the …
M Kandasamy - Naunyn-Schmiedeberg's archives of pharmacology, 2021 - Springer
Abstract Coronavirus disease 2019 (COVID-19) has been characterized by lymphopenia as well as a proinflammatory cytokine storm, which are responsible for the poor prognosis and …
ZY Low, AJW Yip, SK Lal - Biochimica et Biophysica Acta (BBA)-Molecular …, 2022 - Elsevier
Ivermectin (IVM) is an FDA approved macrocyclic lactone compound traditionally used to treat parasitic infestations and has shown to have antiviral potential from previous in-vitro …
AA Samaha, H Mouawia, M Fawaz, H Hassan… - Viruses, 2021 - mdpi.com
Objective: This study was designed to determine the efficacy of ivermectin, an FDA- approved drug, in producing clinical benefits and decreasing the viral load of SARS-CoV-2 …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a major public health issue. COVID-19 is considered an airway/multi-systemic disease, and demise has been …
Despite several studies designed to evaluate the efficacy of chloroquine and hydroxychloroquine in the treatment of coronavirus disease 2019 (COVID-19), there is still …