Diagnosis of early Alzheimer's disease: clinical practice in 2021

AP Porsteinsson, RS Isaacson, S Knox… - The journal of …, 2021 - Springer
Alzheimer's disease is a progressive, irreversible neurodegenerative disease impacting
cognition, function, and behavior. Alzheimer's disease progresses along a continuum from …

Alzheimer's disease–why we need early diagnosis

J Rasmussen, H Langerman - Degenerative neurological and …, 2019 - Taylor & Francis
Alzheimer's disease is the leading cause of dementia. However, neither Alzheimer's disease
nor Alzheimer's dementia are an inevitable consequence of aging. This review provides an …

Subjective cognitive decline: level of risk for future dementia and mild cognitive impairment, a meta-analysis of longitudinal studies

KE Pike, MG Cavuoto, L Li, BJ Wright… - Neuropsychology review, 2022 - Springer
Abstract Subjective Cognitive Decline (SCD) in older adults has been identified as a risk
factor for dementia, although the literature is inconsistent, and it is unclear which factors …

[HTML][HTML] Sex and gender driven modifiers of Alzheimer's: the role for estrogenic control across age, race, medical, and lifestyle risks

A Rahman, H Jackson, H Hristov… - Frontiers in aging …, 2019 - frontiersin.org
Research indicates that after advanced age, the major risk factor for late-onset Alzheimer's
disease is female sex. Out of every three AD patients, two are females with postmenopausal …

Sex-driven modifiers of Alzheimer risk: a multimodality brain imaging study

A Rahman, E Schelbaum, K Hoffman, I Diaz, H Hristov… - Neurology, 2020 - AAN Enterprises
Objective To investigate sex differences in late-onset Alzheimer disease (AD) risks by
means of multimodality brain biomarkers (β-amyloid load via 11C-Pittsburgh compound B …

Artificial intelligence and machine learning in precision medicine: A paradigm shift in big data analysis

M Sahu, R Gupta, RK Ambasta, P Kumar - Progress in molecular biology …, 2022 - Elsevier
The integration of artificial intelligence in precision medicine has revolutionized healthcare
delivery. Precision medicine identifies the phenotype of particular patients with less-common …

Precision Nutrition for Alzheimer's Prevention in ApoE4 Carriers

NG Norwitz, N Saif, IE Ariza, RS Isaacson - Nutrients, 2021 - mdpi.com
The ApoE4 allele is the most well-studied genetic risk factor for Alzheimer's disease, a
condition that is increasing in prevalence and remains without a cure. Precision nutrition …

Brain Health Services: organization, structure, and challenges for implementation. A user manual for Brain Health Services—part 1 of 6

D Altomare, JL Molinuevo, C Ritchie, F Ribaldi… - Alzheimer's research & …, 2021 - Springer
Dementia has a devastating impact on the quality of life of patients and families and comes
with a huge cost to society. Dementia prevention is considered a public health priority by the …

Recognizing novel drugs against Keap1 in Alzheimer's disease using machine learning grounded computational studies

N Mukerjee, K Al-Khafaji, S Maitra… - Frontiers in Molecular …, 2022 - frontiersin.org
Alzheimer's disease (AD) is the most common neurodegenerative disorder in the world,
affecting an estimated 50 million individuals. The nerve cells become impaired and die due …

Diet, microbiota and brain health: unraveling the network intersecting metabolism and neurodegeneration

F Gentile, PE Doneddu, N Riva… - International journal of …, 2020 - mdpi.com
Increasing evidence gives support for the idea that extra-neuronal factors may affect brain
physiology and its predisposition to neurodegenerative diseases. Epidemiological and …