A brief overview of global trends in MSC-based cell therapy

D Jovic, Y Yu, D Wang, K Wang, H Li, F Xu… - Stem cell reviews and …, 2022 - Springer
Human mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or
medicinal signaling cells, are important adult stem cells for regenerative medicine, largely …

Harnessing knee joint resident mesenchymal stem cells in cartilage tissue engineering

X Xu, L Xu, J Xia, C Wen, Y Liang, Y Zhang - Acta Biomaterialia, 2023 - Elsevier
Osteoarthritis (OA) is a widespread clinical disease characterized by cartilage degeneration
in middle-aged and elderly people. Currently, there is no effective treatment for OA apart …

Optimization of mesenchymal stromal cell (MSC) manufacturing processes for a better therapeutic outcome

ME Fernández-Santos, M Garcia-Arranz… - Frontiers in …, 2022 - frontiersin.org
MSCs products as well as their derived extracellular vesicles, are currently being explored
as advanced biologics in cell-based therapies with high expectations for their clinical use in …

[HTML][HTML] Role of regenerative medicine in the treatment of diseases

E Rahmani, M Rezaei, R Tavakoli, E Ghadirzadeh… - Kindle, 2023 - preferpub.org
Regenerative medicine is a rapidly advancing field that aims to restore, replace, or
regenerate damaged tissues and organs using advanced biomedical techniques. Its …

Culture-expanded mesenchymal stromal cell therapy: does it work in knee osteoarthritis? A pathway to clinical success

G Copp, KP Robb, S Viswanathan - Cellular & Molecular Immunology, 2023 - nature.com
Osteoarthritis (OA) is a degenerative multifactorial disease with concomitant structural,
inflammatory, and metabolic changes that fluctuate in a temporal and patient-specific …

3D bioprinting in otolaryngology: A review

A McMillan, N McMillan, N Gupta… - Advanced …, 2023 - Wiley Online Library
The evolution of tissue engineering and 3D bioprinting has allowed for increased
opportunities to generate musculoskeletal tissue grafts that can enhance functional and …

From waste to wealth: Repurposing slaughterhouse waste for xenotransplantation

RL Khan, AA Khraibi, LF Dumée… - … in Bioengineering and …, 2023 - frontiersin.org
Slaughterhouses produce large quantities of biological waste, and most of these materials
are underutilized. In many published reports, the possibility of repurposing this form of waste …

Progress and emerging techniques for biomaterial-based derivation of mesenchymal stem cells (MSCs) from pluripotent stem cells (PSCs)

N Prakash, J Kim, J Jeon, S Kim, Y Arai… - Biomaterials …, 2023 - spj.science.org
The use of mesenchymal stem cells (MSCs) for clinical purposes has skyrocketed in the past
decade. Their multilineage differentiation potentials and immunomodulatory properties have …

Bone marrow mesenchymal stem cells for heart failure treatment: a systematic review and meta-analysis

Y Kalou, AM Al-Khani, KH Haider - Heart, Lung and Circulation, 2023 - Elsevier
Aim Bone marrow-derived mesenchymal stem cells (BM-MSCs) are the most well-studied
and characterised stem cell types. This review was undertaken of the current available …

TWIST1 and TSG6 are coordinately regulated and function as potency biomarkers in human MSCs

RH Lee, SV Boregowda, T Shigemoto-Kuroda… - Science …, 2023 - science.org
Mesenchymal stem/stromal cells (MSCs) have been evaluated in> 1500 clinical trials, but
outcomes remain suboptimal because of knowledge gaps in quality attributes that confer …