Unadjuvanted intranasal spike vaccine elicits protective mucosal immunity against sarbecoviruses
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has
highlighted the need for vaccines that not only prevent disease but also prevent …
highlighted the need for vaccines that not only prevent disease but also prevent …
Myocarditis with COVID-19 mRNA vaccines
Myocarditis has been recognized as a rare complication of coronavirus disease 2019
(COVID-19) mRNA vaccinations, especially in young adult and adolescent males. According …
(COVID-19) mRNA vaccinations, especially in young adult and adolescent males. According …
The efficacy and effectiveness of the COVID-19 vaccines in reducing infection, severity, hospitalization, and mortality: a systematic review
I Mohammed, A Nauman, P Paul… - Human vaccines & …, 2022 - Taylor & Francis
With the relatively rapid development of the COVID-19 pandemic, vaccine development has
become crucial for limiting disease transmission. The accelerated growth in the approved …
become crucial for limiting disease transmission. The accelerated growth in the approved …
Efficacy and safety of an inactivated whole-virion SARS-CoV-2 vaccine (CoronaVac): interim results of a double-blind, randomised, placebo-controlled, phase 3 trial in …
MD Tanriover, HL Doğanay, M Akova, HR Güner… - The Lancet, 2021 - thelancet.com
Background CoronaVac, an inactivated whole-virion SARS-CoV-2 vaccine, has been shown
to be well tolerated with a good safety profile in individuals aged 18 years and older in …
to be well tolerated with a good safety profile in individuals aged 18 years and older in …
Safety and efficacy of NVX-CoV2373 Covid-19 vaccine
PT Heath, EP Galiza, DN Baxter, M Boffito… - … England Journal of …, 2021 - Mass Medical Soc
Background Early clinical data from studies of the NVX-CoV2373 vaccine (Novavax), a
recombinant nanoparticle vaccine against severe acute respiratory syndrome coronavirus 2 …
recombinant nanoparticle vaccine against severe acute respiratory syndrome coronavirus 2 …
Circulating spike protein detected in post–COVID-19 mRNA vaccine myocarditis
Background: Cases of adolescents and young adults developing myocarditis after
vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted …
vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted …
Vaccine adjuvants: mechanisms and platforms
T Zhao, Y Cai, Y Jiang, X He, Y Wei, Y Yu… - Signal transduction and …, 2023 - nature.com
Adjuvants are indispensable components of vaccines. Despite being widely used in
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
vaccines, their action mechanisms are not yet clear. With a greater understanding of the …
[HTML][HTML] SARS-CoV-2 mRNA vaccines induce persistent human germinal centre responses
JS Turner, JA O'Halloran, E Kalaidina, W Kim… - Nature, 2021 - nature.com
Abstract SARS-CoV-2 mRNA-based vaccines are about 95% effective in preventing COVID-
19 1, 2, 3, 4, 5. The dynamics of antibody-secreting plasmablasts and germinal centre B …
19 1, 2, 3, 4, 5. The dynamics of antibody-secreting plasmablasts and germinal centre B …
Efficacy and safety of a recombinant plant-based adjuvanted Covid-19 vaccine
KJ Hager, G Pérez Marc, P Gobeil… - New England journal …, 2022 - Mass Medical Soc
Abstract Background Coronavirus-like particles (CoVLP) that are produced in plants and
display the prefusion spike glycoprotein of the original strain of severe acute respiratory …
display the prefusion spike glycoprotein of the original strain of severe acute respiratory …
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
M Sadarangani, A Marchant… - Nature Reviews …, 2021 - nature.com
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …