Leishmaniasis is a neglected tropical disease that has a wide spectrum of clinical
manifestations, ranging from visceral to cutaneous, with millions of new cases and …

Leishmania is a trypanosomatid that causes leishmaniasis. It is transmitted to vertebrate
hosts during the blood meal of phlebotomine sandflies. The clinical manifestations of the …

Cystic echinococcosis, an endemic zoonosis in Algeria, is caused by the development of the
helminth Echinococcus granulosus. Surgery remains the main treatment despite inducing …

A growing number of studies have demonstrated the in vitro potential of an impressive
number of antileishmanial candidates in the past years. However, the lack of uniformity …

Chagas disease (CD) is a neglected tropical disease of worldwide health concern, caused
by the flagellate protozoan Trypanosoma cruzi (T. cruzi), endemic in Latin America and …

Drug therapy for leishmaniasis remains a major challenge as currently available drugs have
limited efficacy, induce serious side-effects and are not accessible to everyone. Thus, the …

Breast cancer is a high-magnitude public health problem, continually challenging physicians
and scientists worldwide in the field of drug therapy. 4-nitrochalcone (4NC) is a phenolic …

Chagas disease affects 7 million people worldwide and is endemic in 20 Latin American
countries. It is estimated to cause about 14,000 deaths annually and more than 75 million …

Aim: To access the metabolic changes caused by a chalcone derivative (LabMol-75)
through a proteomic approach. Methods: Proteomic analysis was performed after 9 h of …

Leishmaniasis disease is a serious public health problem. This disease reaches about 10 to
12 million people, and 20–30 thousand people die yearly. The disease treatment is realized …