Importance Eosinophilic esophagitis (EoE) is a chronic immune-mediated inflammatory
disease of the esophagus that affects an estimated 34.4/100 000 people in Europe and …

The functional lumen imaging probe (FLIP) measures luminal dimensions using impedance
planimetry, performed most often during sedated upper endoscopy. Mechanical properties …

Esophageal symptoms are common and may indicate the presence of gastroesophageal
reflux disease (GERD), structural processes, motor dysfunction, behavioral conditions, or …

Eosinophilic esophagitis (EoE) is an eosinophil-rich, TH 2 antigen–mediated disease of
increasing pediatric and adult worldwide prevalence. Diagnosis requires greater than or …

BACKGROUND: Eosinophilic esophagitis (EoE) is a chronic esophageal inflammation that
may lead to stricture formation. This narrowing can cause major complications including …

While the diagnosis and initial treatment of eosinophilic esophagitis are becoming more
standardized, there are still major gaps in knowledge related to measuring treatment …

Background & Aims Identification of fibrosis in pediatric eosinophilic esophagitis (EoE) relies
on symptom assessment and endoscopy. Symptoms are highly variable, and early fibrotic …

The techniques used to measure esophageal and sphincter physiology have evolved over
time with high-resolution manometry and the functional luminal imaging probe (FLIP) taking …

Background Esophageal remodeling is a factor in disease progression and symptom
severity for patients with eosinophilic esophagitis (EoE). Remodeling can begin early in …

Background & Aims Evaluation and treatment of children with eosinophilic esophagitis (EoE)
requires serial endoscopic, visual, and histologic assessment by sedated …