Motivation: The sequencing of the human genome has made it possible to identify an
informative set of> 1 million single nucleotide polymorphisms (SNPs) across the genome …

Streptococcus pneumoniae and Neisseria meningitidis can cause sepsis and meningitis.
Several risk factors for pneumococcal and meningococcal disease have been identified, but …

Genome‐wide scans of nucleotide variation in human subjects are providing an increasing
number of replicated associations with complex disease traits. Most of the variants detected …

A Statistical Approach to Genetic Epidemiology After studying statistics and mathematics at
the University of Munich and obtaining his doctoral degree from the University of Dortmund …

This chapter is a comprehensive review of quality control (QC) methods for SNP-based
genotyping panels used in genome-wide association studies. These include QC on …

In the past few years, genome-wide association study (GWAS) has made great successes in
identifying genetic susceptibility loci underlying many complex diseases and traits. The …

Background Genomic selection has gained much attention and the main goal is to increase
the predictive accuracy and the genetic gain in livestock using dense marker information …

Background Alzheimer's disease (AD) is the most common cause of dementia in the elderly
and the sixth leading cause of death in the United States. AD is mainly considered a …

In current genome‐wide association studies (GWAS), the analysis is usually focused on
autosomal variants only, and the sex chromosomes are often neglected. Recently, a number …

Abstract Knowledge on the impact of pharmacogenetics in predicting outcome and toxicity in
diffuse large B-cell lymphoma (DLBCL) is scant. We tested 106 consecutive DLBCL treated …