INTRODUCTION Across human societies and in both sexes, some 2 to 10% of individuals report engaging in sex with same-sex partners, either exclusively or in addition to sex with …
Genome-wide association studies (GWAS) have identified thousands of genetic variants associated with human complex traits. However, the genes or functional DNA elements …
NYA Sey, B Hu, W Mah, H Fauni, JC McAfee… - Nature …, 2020 - nature.com
Most risk variants for brain disorders identified by genome-wide association studies reside in the noncoding genome, which makes deciphering biological mechanisms difficult. A …
DA Kia, D Zhang, S Guelfi, C Manzoni… - JAMA …, 2021 - jamanetwork.com
Importance Substantial genome-wide association study (GWAS) work in Parkinson disease (PD) has led to the discovery of an increasing number of loci shown reliably to be associated …
Disease variants identified by genome-wide association studies (GWAS) tend to overlap with expression quantitative trait loci (eQTLs), but it remains unclear whether this overlap is …
Nanoscience has emerged as a fascinating field of science, with its implementation in multiple applications in the form of nanotechnology. Nanotechnology has recently been …
In cross-platform analyses of 174 metabolites, we identify 499 associations (P< 4.9× 10− 10) characterized by pleiotropy, allelic heterogeneity, large and nonlinear effects and …
Mosaic loss of chromosome Y (LOY) in circulating white blood cells is the most common form of clonal mosaicism,,,–, yet our knowledge of the causes and consequences of this is …
B Li, MD Ritchie - Frontiers in Genetics, 2021 - frontiersin.org
Since their inception, genome-wide association studies (GWAS) have identified more than a hundred thousand single nucleotide polymorphism (SNP) loci that are associated with …