[HTML][HTML] Mitochondria-targeted antioxidants, an innovative class of antioxidant compounds for neurodegenerative diseases: perspectives and limitations

M Fields, A Marcuzzi, A Gonelli, C Celeghini… - International journal of …, 2023 - mdpi.com
Neurodegenerative diseases comprise a wide spectrum of pathologies characterized by
progressive loss of neuronal functions and structures. Despite having different genetic …

[HTML][HTML] Cardiac damage in autoimmune diseases: Target organ involvement that cannot be ignored

SY Pan, HM Tian, Y Zhu, WJ Gu, H Zou… - Frontiers in …, 2022 - frontiersin.org
Autoimmune diseases are diseases that cause damage to the body's own tissues as a result
of immune dysfunction, often involving multiple organs and systems. The heart is one of the …

[HTML][HTML] Aging Process and Related Diseases

F Taheri, E Rahmani, SS Fard, M Rezaei, A Ayati… - Kindle, 2023 - preferpub.org
The aging process is a complex biological phenomenon that results in the gradual decline of
physiological function and an increased risk of age-related diseases. While aging is a …

[HTML][HTML] Associations of neuroinflammatory IL-6 and IL-8 with brain atrophy, memory decline, and core AD biomarkers–in cognitively unimpaired older adults

E Capogna, LO Watne, Ø Sørensen… - Brain, Behavior, and …, 2023 - Elsevier
Concentrations of pro-inflammatory cytokines–interleukin-6 (IL-6) and interleukin-8 (IL-8)–
are increased with age and in Alzheimer's disease (AD). It is not clear whether …

[HTML][HTML] Vascular ageing: mechanisms, risk factors, and treatment strategies

J Ya, U Bayraktutan - International Journal of Molecular Sciences, 2023 - mdpi.com
Ageing constitutes the biggest risk factor for poor health and adversely affects the integrity
and function of all the cells, tissues, and organs in the human body. Vascular ageing …

[HTML][HTML] Thymic exhaustion and increased immune activation are the main mechanisms involved in impaired immunological recovery of HIV-positive patients under …

MC Dos Santos Guedes, WHV Carvalho-Silva… - Viruses, 2023 - mdpi.com
Decades of studies in antiretroviral therapy (ART) have passed, and the mechanisms that
determine impaired immunological recovery in HIV-positive patients receiving ART have not …

[HTML][HTML] Respiratory infections in the aging lung: implications for diagnosis, therapy, and prevention

A Häder, N Köse-Vogel, L Schulz, L Mlynska… - Aging and …, 2023 - ncbi.nlm.nih.gov
Respiratory infections pose a significant health problem among elderly individuals,
particularly during the COVID-19 pandemic. The increased mortality and morbidity rates …

[HTML][HTML] Polyphenols: Immunonutrients tipping the balance of immunometabolism in chronic diseases

C Ferreira, P Vieira, H Sá, J Malva… - Frontiers in …, 2024 - frontiersin.org
Mounting evidence progressively appreciates the vital interplay between immunity and
metabolism in a wide array of immunometabolic chronic disorders, both autoimmune and …

[HTML][HTML] Immunosenescence and skin: a state of art of its etiopathogenetic role and crucial watershed for systemic implications

V Papa, F Li Pomi, F Borgia, M Vaccaro… - International Journal of …, 2023 - mdpi.com
Immunosenescence is a complex multifactorial phenomenon consisting of wide-ranging
remodeling of the immune system during the life span, resulting in an age-related qualitative …

[HTML][HTML] Secondary central nervous system demyelinating disorders in the elderly: A narrative review

C Bakirtzis, M Lima, SS De Lorenzo, A Artemiadis… - Healthcare, 2023 - mdpi.com
Secondary demyelinating diseases comprise a wide spectrum group of pathological
conditions and may either be attributed to a disorder primarily affecting the neurons or …