Nascent pharmacological advancement in adamantane derivatives

A Ragshaniya, V Kumar, RK Tittal… - Archiv der Pharmazie, 2024 - Wiley Online Library
The adamantane moiety has attracted significant attention since its discovery in 1933 due to
its remarkable structural, chemical, and medicinal properties. This molecule has a notable …

Animal models for studying coronavirus infections and developing antiviral agents and vaccines

Q Lin, C Lu, Y Hong, R Li, J Chen, W Chen, J Chen - Antiviral Research, 2022 - Elsevier
In addition to severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East
respiratory syndrome coronavirus (MERS-CoV), SARS-CoV-2 has become the third deadly …

[HTML][HTML] Transcriptome-based analysis of human peripheral blood reveals regulators of immune response in different viral infections

SM Ivanov, OA Tarasova, VV Poroikov - Frontiers in Immunology, 2023 - frontiersin.org
Introduction There are difficulties in creating direct antiviral drugs for all viruses, including
new, suddenly arising infections, such as COVID-19. Therefore, pathogenesis-directed …

[HTML][HTML] The potential of IFN-λ, IL-32γ, IL-6, and IL-22 as safeguards against human viruses: a systematic review and a meta-analysis

AA Sattar, A Qaiser, H Kausar, S Aqil… - Frontiers in …, 2024 - frontiersin.org
Many studies have investigated the antiviral activity of cytokines, including interleukin-6 (IL-
6), interleukin-22 (IL-22), interleukin-32 gamma (IL-32γ), and interferon-lambda (IFN-λ) in …

[HTML][HTML] A potent virucidal activity of functionalized TiO2 nanoparticles adsorbed with flavonoids against SARS-CoV-2

G León-Gutiérrez, JE Elste, C Cabello-Gutiérrez… - Applied Microbiology …, 2022 - Springer
The coronavirus SARS-CoV-2 has caused a pandemic with> 550 millions of cases and> 6
millions of deaths worldwide. Medical management of COVID-19 relies on supportive care …

[HTML][HTML] Design and synthesis of novel 5-((3-(Trifluoromethyl) piperidin-1-yl) sulfonyl) indoline-2, 3-dione derivatives as promising Antiviral agents: in vitro, in silico …

RR Ezz Eldin, MA Saleh, SA Alwarsh, A Rushdi… - Pharmaceuticals, 2023 - mdpi.com
Herein, a series of new isatin derivatives was designed and synthesized (1–9) as broad-
spectrum antiviral agents. Consequently, the antiviral activities of the synthesized …

[HTML][HTML] Instantaneous inactivation of herpes simplex virus by silicon nitride bioceramics

G Pezzotti, E Ohgitani, S Ikegami, M Shin-Ya… - International Journal of …, 2023 - mdpi.com
Hydrolytic reactions taking place at the surface of a silicon nitride (Si3N4) bioceramic were
found to induce instantaneous inactivation of Human herpesvirus 1 (HHV-1, also known as …

[HTML][HTML] Secondary metabolites of Bacillus subtilis L2 show antiviral activity against pseudorabies virus

X Wang, G Hao, M Zhou, M Chen, H Ling… - Frontiers in …, 2023 - frontiersin.org
Bacillus subtilis (B. subtilis) is a commercially important probiotic known to produce
secondary metabolites with antibacterial, antifungal and anti-inflammatory activities …

[HTML][HTML] Lavandula austroapennina: Assessment of the Antiviral Activity of Lipophilic Extracts from Its Organs

A Chianese, C Gravina, MV Morone, A Ambrosino… - Viruses, 2023 - mdpi.com
In a framework aimed at the recovery and enhancement of medicinal plants endemic to the
territory of the Cilento and Vallo di Diano National Park, Lavandula austroapennina NG …

[HTML][HTML] Plantaricin NC8 αβ rapidly and efficiently inhibits flaviviruses and SARS-CoV-2 by disrupting their envelopes

AAM Omer, J Hinkula, PTH Tran, W Melik, E Zattarin… - Plos one, 2022 - journals.plos.org
Potent broad-spectrum antiviral agents are urgently needed to combat existing and
emerging viral infections. This is particularly important considering that vaccine development …