Decades of research have identified genetic factors and biochemical pathways involved in
neurodegenerative diseases (NDDs). We present evidence for the following eight hallmarks …

Understanding communication and information processing in nervous systems is a central
goal of neuroscience. Over the past two decades, advances in connectomics and network …

The pathology of Alzheimer disease (AD) damages structural and functional brain networks,
resulting in cognitive impairment. The results of recent connectomics studies have now …

Since the second half of the twentieth century, intracranial electroencephalography (iEEG),
including both electrocorticography (ECoG) and stereo-electroencephalography (sEEG) …

Background: Analysis of the human connectome using functional magnetic resonance
imaging (fMRI) started in the mid-1990s and attracted increasing attention in attempts to …

Noninvasive medical neuroimaging has yielded many discoveries about the brain
connectivity. Several substantial techniques mapping morphological, structural and …

The cortico–basal ganglia–thalamo–cortical loop is one of the fundamental network motifs in
the brain. Revealing its structural and functional organization is critical to understanding …

Diffusion magnetic resonance imaging (dMRI) tractography is an advanced imaging
technique that enables in vivo reconstruction of the brain's white matter connections at …

Brain diseases, including tumors and mental and neurological disorders, seriously threaten
the health and well-being of millions of people worldwide. Structural and functional …

Numerous brain disorders demonstrate structural brain abnormalities, which are thought to
arise from molecular perturbations or connectome miswiring. The unique and shared …