Pseudomonas aeruginosa is the microorganism most frequently involved in the main ICU-
acquired infections, with special importance in ventilator associated pneumonia. Its …

It is evident that the admission of some patients with sepsis and septic shock to hospitals is
occurring late in their illness, which has contributed to the increase in poor outcomes and …

Introduction The recent discovery of TAK981 (Subasumstat), the first-in-class selective
inhibitor of SUMOylation, enables new immune treatments. TAK981 is already in clinical …

The emergence of multidrug-resistant (MDR) Klebsiella pneumoniae strains causes severe
problems in the treatment of bacterial infections owing to limited treatment options …

Sepsis is one of the leading causes of death worldwide. While mortality is high regardless of
inciting infection or comorbidities, mortality in patients with cancer and sepsis is significantly …

Acute kidney injury (AKI) is a life-threatening condition characterized by a rapid and
transient decrease in kidney function. AKI is part of an array of conditions collectively defined …

Background: Elderly cancer patients are more predisposed to developing nosocomial
infections during anti-neoplastic treatment, and are associated with a bleaker prognosis …

Sepsis, the most serious complication of infection, occurs when a cascade of potentially life-
threatening inflammatory responses is triggered. Potentially life-threatening septic shock is a …

Introduction: Immunosuppressed patients with bloodstream infection is at risk of mortality.
Our objective was to assess the independent risk factors of bloodstream infection with …

Background The use of fluoroquinolones to prevent infections in neutropenic patients with
cancer or undergoing hematopoietic stem cell transplantation (HSCT) is a controversial …