[HTML][HTML] Global colorectal cancer burden in 2020 and projections to 2040

Y Xi, P Xu - Translational oncology, 2021 - Elsevier
As the third most common malignancy and the second most deadly cancer, colorectal
cancer (CRC) induces estimated 1.9 million incidence cases and 0.9 million deaths …

Clinical value of consensus molecular subtypes in colorectal cancer: a systematic review and meta-analysis

S Ten Hoorn, TR de Back… - JNCI: Journal of the …, 2022 - academic.oup.com
Background The consensus molecular subtypes (CMSs) of colorectal cancer (CRC) capture
tumor heterogeneity at the gene-expression level. Currently, a restricted number of …

Machine learning-based integration develops an immune-derived lncRNA signature for improving outcomes in colorectal cancer

Z Liu, L Liu, S Weng, C Guo, Q Dang, H Xu… - Nature …, 2022 - nature.com
Long noncoding RNAs (lncRNAs) are recently implicated in modifying immunology in
colorectal cancer (CRC). Nevertheless, the clinical significance of immune-related lncRNAs …

Circadian rhythm-related genes index: A predictor for HNSCC prognosis, immunotherapy efficacy, and chemosensitivity

H Chi, J Yang, G Peng, J Zhang, G Song, X Xie… - Frontiers in …, 2023 - frontiersin.org
Background Head and neck squamous cell carcinoma (HNSCC) is the most common head
and neck cancer and is highly aggressive and heterogeneous, leading to variable prognosis …

Cuproptosis-associated lncRNA establishes new prognostic profile and predicts immunotherapy response in clear cell renal cell carcinoma

S Xu, D Liu, T Chang, X Wen, S Ma, G Sun… - Frontiers in …, 2022 - frontiersin.org
Background: Clear cell renal cell carcinoma (ccRCC) accounts for 80% of all kidney cancers
and has a poor prognosis. Recent studies have shown that copper-dependent, regulated …

[HTML][HTML] Immune-related lncRNA to construct novel signature and predict the immune landscape of human hepatocellular carcinoma

W Hong, L Liang, Y Gu, Z Qi, H Qiu, X Yang… - … Therapy-Nucleic Acids, 2020 - cell.com
The signature composed of immune-related long noncoding ribonucleic acids (irlncRNAs)
with no requirement of specific expression level seems to be valuable in predicting the …

Cuprotosis programmed-cell-death-related lncRNA signature predicts prognosis and immune landscape in PAAD patients

H Chi, G Peng, R Wang, F Yang, X Xie, J Zhang, K Xu… - Cells, 2022 - mdpi.com
In terms of mortality and survival, pancreatic cancer is one of the worst malignancies. Known
as a unique type of programmed cell death, cuprotosis contributes to tumor cell growth …

Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer

Z Liu, CG Guo, Q Dang, L Wang, L Liu, S Weng, H Xu… - …, 2022 - thelancet.com
Summary Background Long non-coding RNAs (lncRNAs) have recently emerged as
essential biomarkers of cancer progression. However, studies are limited regarding …

Machine learning to construct sphingolipid metabolism genes signature to characterize the immune landscape and prognosis of patients with uveal melanoma

H Chi, G Peng, J Yang, J Zhang, G Song… - Frontiers in …, 2022 - frontiersin.org
Background Uveal melanoma (UVM) is the most common primary intraocular malignancy in
adults and is highly metastatic, resulting in a poor patient prognosis. Sphingolipid …

By integrating single-cell RNA-seq and bulk RNA-seq in sphingolipid metabolism, CACYBP was identified as a potential therapeutic target in lung adenocarcinoma

P Zhang, S Pei, Z Gong, Y Feng, X Zhang… - Frontiers in …, 2023 - frontiersin.org
Background Lung adenocarcinoma (LUAD) is a heterogeneous disease with a dismal
prognosis for advanced tumors. Immune-associated cells in the microenvironment …