[HTML][HTML] Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications

F Zhang, RI Lau, Q Liu, Q Su, FKL Chan… - Nature Reviews …, 2023 - nature.com
The gastrointestinal tract is involved in coronavirus disease 2019 (COVID-19) caused by
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The gut microbiota has …

[HTML][HTML] Antimicrobial resistance and COVID-19: Intersections and implications

GM Knight, RE Glover, CF McQuaid, ID Olaru… - Elife, 2021 - elifesciences.org
Before the coronavirus 2019 (COVID-19) pandemic began, antimicrobial resistance (AMR)
was among the top priorities for global public health. Already a complex challenge, AMR …

[HTML][HTML] Global antibiotic use during the COVID-19 pandemic: analysis of pharmaceutical sales data from 71 countries, 2020–2022

A Nandi, S Pecetta, DE Bloom - EClinicalMedicine, 2023 - thelancet.com
Background Despite bacterial coinfection rates of less than 10%, antibiotics are prescribed
to an estimated 75% of patients with COVID-19, potentially exacerbating antimicrobial …

[HTML][HTML] Co-infections, secondary infections, and antimicrobial use in patients hospitalised with COVID-19 during the first pandemic wave from the ISARIC WHO CCP …

CD Russell, CJ Fairfield, TM Drake, L Turtle… - The Lancet …, 2021 - thelancet.com
Background Microbiological characterisation of co-infections and secondary infections in
patients with COVID-19 is lacking, and antimicrobial use is high. We aimed to describe …

[HTML][HTML] Antibiotic resistance associated with the COVID-19 pandemic: a systematic review and meta-analysis

BJ Langford, JPR Soucy, V Leung, M So… - Clinical Microbiology …, 2023 - Elsevier
Background COVID-19 and antimicrobial resistance (AMR) are two intersecting global
public health crises. Objective We aimed to describe the impact of the COVID-19 pandemic …

[HTML][HTML] Altered oral and gut microbiota and its association with SARS-CoV-2 viral load in COVID-19 patients during hospitalization

Y Wu, X Cheng, G Jiang, H Tang, S Ming… - npj Biofilms and …, 2021 - nature.com
The human oral and gut commensal microbes play vital roles in the development and
maintenance of immune homeostasis, while its association with susceptibility and severity of …

Metallo-β-lactamases in the age of multidrug resistance: from structure and mechanism to evolution, dissemination, and inhibitor design

G Bahr, LJ Gonzalez, AJ Vila - Chemical Reviews, 2021 - ACS Publications
Antimicrobial resistance is one of the major problems in current practical medicine. The
spread of genes coding for resistance determinants among bacteria challenges the use of …

[HTML][HTML] Antimicrobial resistance (AMR) in COVID-19 patients: a systematic review and meta-analysis (November 2019–June 2021)

RM Kariyawasam, DA Julien, DC Jelinski… - … Resistance & Infection …, 2022 - Springer
Abstract Background Pneumonia from SARS-CoV-2 is difficult to distinguish from other viral
and bacterial etiologies. Broad-spectrum antimicrobials are frequently prescribed to patients …

[HTML][HTML] Strategies to improve antimicrobial utilization with a special focus on developing countries

B Godman, A Egwuenu, M Haque, OO Malande… - Life, 2021 - mdpi.com
Antimicrobial resistance (AMR) is a high priority across countries as it increases morbidity,
mortality and costs. Concerns with AMR have resulted in multiple initiatives internationally …

[HTML][HTML] Antimicrobial resistance in patients with COVID-19: a systematic review and meta-analysis

BJ Langford, M So, M Simeonova, V Leung, J Lo… - The Lancet …, 2023 - thelancet.com
Background Frequent use of antibiotics in patients with COVID-19 threatens to exacerbate
antimicrobial resistance. We aimed to establish the prevalence and predictors of bacterial …