Mycobacterium tuberculosis Transmission in High-Incidence Settings—New Paradigms and Insights
Tuberculosis has affected humankind for thousands of years, but a deeper understanding of
its cause and transmission only arose after Robert Koch discovered Mycobacterium …
its cause and transmission only arose after Robert Koch discovered Mycobacterium …
Classification of early tuberculosis states to guide research for improved care and prevention: an international Delphi consensus exercise
The current active–latent paradigm of tuberculosis largely neglects the documented
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …
spectrum of disease. Inconsistency with regard to definitions, terminology, and diagnostic …
The impact of alternative delivery strategies for novel tuberculosis vaccines in low-income and middle-income countries: a modelling study
Background Tuberculosis is a leading infectious cause of death worldwide. Novel vaccines
will be required to reach global targets and reverse setbacks resulting from the COVID-19 …
will be required to reach global targets and reverse setbacks resulting from the COVID-19 …
New tuberculosis vaccines in India: modelling the potential health and economic impacts of adolescent/adult vaccination with M72/AS01E and BCG-revaccination
RA Clark, CK Weerasuriya, A Portnoy, C Mukandavire… - BMC medicine, 2023 - Springer
Background India had an estimated 2.9 million tuberculosis cases and 506 thousand deaths
in 2021. Novel vaccines effective in adolescents and adults could reduce this burden …
in 2021. Novel vaccines effective in adolescents and adults could reduce this burden …
Disease transmission by patients with subclinical tuberculosis
HV Nguyen, E Tiemersma, NV Nguyen… - Clinical Infectious …, 2023 - academic.oup.com
Background Subclinical tuberculosis has been increasingly recognized as a separate state
in the spectrum of the disease. However, evidence on the transmissibility of subclinical …
in the spectrum of the disease. However, evidence on the transmissibility of subclinical …
[HTML][HTML] Asymptomatic but infectious–The silent driver of pathogen transmission. A pragmatic review
N Shaikh, P Swali, RMGJ Houben - Epidemics, 2023 - Elsevier
Abstract Throughout 2020, COVID-19 interventions prioritised symptomatic individuals
despite growing evidence of pre-symptomatic and asymptomatic transmission. From the …
despite growing evidence of pre-symptomatic and asymptomatic transmission. From the …
Finding and treating both tuberculosis disease and latent infection during population-wide active case finding for tuberculosis elimination
In recognition of the high rates of undetected tuberculosis in the community, the World
Health Organization (WHO) encourages targeted active case finding (ACF) among “high …
Health Organization (WHO) encourages targeted active case finding (ACF) among “high …
Reevaluating progression and pathways following Mycobacterium tuberculosis infection within the spectrum of tuberculosis
KC Horton, AS Richards, JC Emery… - Proceedings of the …, 2023 - National Acad Sciences
Traditional understanding of the risk of progression from Mycobacterium tuberculosis (Mtb)
infection to tuberculosis (TB) overlooks diverse presentations across a spectrum of disease …
infection to tuberculosis (TB) overlooks diverse presentations across a spectrum of disease …
Population-wide active case finding as a strategy to end TB
Tuberculosis (TB) is the leading infectious cause of morbidity and mortality globally. Despite
available tools for preventing, finding, and treating TB, many people with TB remain …
available tools for preventing, finding, and treating TB, many people with TB remain …
Subclinical tuberculosis: a meta-analysis of prevalence and scoping review of definitions, prevalence and clinical characteristics
Background: This scoping review aimed to characterise definitions used to describe
subclinical tuberculosis (TB), estimate the prevalence in different populations and describe …
subclinical tuberculosis (TB), estimate the prevalence in different populations and describe …