The Wistar-Kyoto rat model of endogenous depression: A tool for exploring treatment resistance with an urgent need to focus on sex differences

SJ Millard, K Weston-Green, KA Newell - Progress in Neuro …, 2020 - Elsevier
Major depressive disorder (MDD) is one of the leading causes of years lived with disability
and contributor to the burden of disease worldwide. The incidence of MDD has increased …

[HTML][HTML] How obstructed action efficacy impacts reward-based decision making in adolescent depression: an Fmri study

KM Harlé, TC Ho, CG Connolly, A Simmons… - Journal of the American …, 2023 - Elsevier
Objective Disruption of reward seeking behavior by unforeseen obstacles can promote
negative affect, including frustration and irritability, in adolescents. Repeated experiences of …

Shared and specific dynamics of brain segregation and integration in bipolar disorder and major depressive disorder: a resting-state functional magnetic resonance …

Z Luo, G Chen, Y Jia, S Zhong, J Gong, F Chen… - Journal of Affective …, 2021 - Elsevier
Background When bipolar disorder (BD) presents as the depressive state, it is often
misdiagnosed as major depressive disorder (MDD). However, few studies have focused on …

Clinical utility of a short resting‐state MRI scan in differentiating bipolar from unipolar depression

M Li, T Das, W Deng, Q Wang, Y Li… - Acta Psychiatrica …, 2017 - Wiley Online Library
Objective Depression in bipolar disorder (BipD) requires a therapeutic approach that is from
treating unipolar major depressive disorder (UniD), but to date, no reliable methods could …

Baseline brain perfusion and brain structure in patients with major depression: a multimodal magnetic resonance imaging study

N Vasic, ND Wolf, G Grön, Z Sosic-Vasic… - Journal of Psychiatry and …, 2015 - jpn.ca
Background: Abnormal regional cerebral blood flow (rCBF) and grey matter volume have
been frequently reported in patients with major depressive disorder (MDD). However, it is …

Abnormal voxel-wise whole-brain functional connectivity in first-episode, drug-naive adolescents with major depression disorder

R Zheng, Y Chen, Y Jiang, B Zhou, S Han… - European child & …, 2023 - Springer
Major depression disorder (MDD) is one of the most common psychiatric disorders. Previous
studies have demonstrated structural and functional abnormalities in adult depression …

The development of an RDoC-based treatment program for adolescent depression:“Training for Awareness, Resilience, and Action”(TARA)

E Henje Blom, LG Duncan, TC Ho… - Frontiers in human …, 2014 - frontiersin.org
Major depressive disorder (MDD) is one of the current leading causes of disability
worldwide. Adolescence is a vulnerable period for the onset of depression, with MDD …

Cerebral blood flow changes and their genetic mechanisms in major depressive disorder: a combined neuroimaging and transcriptome study

X Sun, W Huang, J Wang, R Xu, X Zhang… - Psychological …, 2023 - cambridge.org
BackgroundExtensive research has shown abnormal cerebral blood flow (CBF) in patients
with major depressive disorder (MDD) that is a heritable disease. The objective of this study …

Bipolar disorder and the vascular system: mechanisms and new prevention opportunities

BI Goldstein - Canadian Journal of Cardiology, 2017 - Elsevier
Bipolar disorder (BD) is associated with excessive prevalence and premature onset of
cardiovascular disease (CVD). This association is observed internationally in clinical as well …

Altered insular activation and increased insular functional connectivity during sad and happy face processing in adolescent major depressive disorder

EH Blom, CG Connolly, TC Ho, KZ LeWinn… - Journal of Affective …, 2015 - Elsevier
Background Major depressive disorder (MDD) is a leading cause of disability worldwide and
occurs commonly first during adolescence. The insular cortex (IC) plays an important role in …