The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

Cancer is the second cause of death worldwide, surpassed only by cardiovascular diseases,
due to the lack of early diagnosis, and high relapse rate after conventional therapies …

Circular RNAs (circRNAs) are involved in the development of various diseases, but there is
little knowledge of circRNAs in osteoarthritis (OA). The aim of study was to identify circRNA …

Cancer is a global public health concern. Alterations in epigenetic processes are among the
earliest genomic aberrations occurring during cancer development and are closely related …

Extracellular vesicles (EVs) are specialised endogenous carriers of proteins and nucleic
acids and are involved in intercellular communication. EVs are therefore proposed as …

Nucleic acid therapeutics are rapidly expanding because of recent advancements in
production and purification. This class of therapeutics may change the field of disease …

The highly specific induction of RNA interference-mediated gene knockdown, based on the
direct application of small interfering RNAs (siRNAs), opens novel avenues towards …

Bone injuries and diseases constitute a burden both socially and economically, as the
consequences of a lack of effective treatments affect both the patients' quality of life and the …

Silk is a natural polymer with unique physicochemical and mechanical properties which
makes it a desirable biomaterial for biomedical and pharmaceutical applications. Silk fibroin …

Abstract Coronavirus disease 2019 (COVID‐19) is the seventh member of the bat severe
acute respiratory syndrome family. COVID‐19 can fuse their envelopes with the host cell …