This paper reviews advances in epilepsy in recent years with an emphasis on therapeutics
and underlying mechanisms, including status epilepticus, drug and surgical treatments …

Neurosurgery is an underutilized treatment that can potentially cure drug‐refractory
epilepsy. Careful, multidisciplinary presurgical evaluation is vital for selecting patients and to …

Temporal lobe epilepsy (TLE) is the most common focal epilepsy in adults. TLE has a high
chance of becoming medically refractory, and as such, is frequently considered for further …

Abstract Background and Objectives: Epilepsy is a clinical phenomenon caused by sudden
abnormal and excessive discharge of brain neurons. It affects around 70 million people all …

Objective Although most temporal lobe epilepsy (TLE) patients show marked hippocampal
sclerosis (HS) upon pathological examination, 40% present with no significant cell loss but …

Mesial temporal lobe epilepsy (MTLE) with hippocampus sclerosis (HS) is associated with
functional and structural alterations extending beyond the temporal regions and abnormal …

Hippocampal sclerosis (HS) is considered the most frequent neuropathological finding in
patients with mesial temporal lobe epilepsy (MTLE). Hippocampal specimens of …

Human neuroimaging has had a major impact on the biological understanding of epilepsy
and the relationship between pathophysiology, seizure management, and outcomes. This …

Objectives To investigate the presence and progression of gray matter (GM) reduction in
seizure‐free patients with temporal lobe epilepsy (TLE). Methods We enrolled 39 …

Objective Hippocampal sclerosis (HS), the most common cause of refractory temporal lobe
epilepsy, is associated with hippocampal volume loss and increased T2 signal. These can …